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Latest Appetite Stories

2009-09-03 15:52:31

Leptin-serotonin pathway offers new clues for obesity and osteoporosis prevention New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual. The research, which explains how leptin "“ well-known appetite-suppressing hormone "“ acts in the brain, is published in the Sept. 4 issue of Cell. When the leptin-serotonin pathway is turned on in mice, the...

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2009-09-01 11:55:00

Some of the first information about how fat causes hypertension have been identified by researchers who say the findings should one day help identify which obese people "“ and maybe some thin ones too "“ are at risk for hypertension and which drugs would work best for them.Medical College of Georgia researchers have found that deleting or mutating the gene PTP1B puts mice at risk for hypertension by interfering with an endogenous mechanism that should help prevent it. The findings...

2009-08-05 11:32:59

As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat.The researchers describe for the first time a new bunch of leptin-responsive (LepRb) neurons in the brain's lateral hypothalamic area (LHA). Those LHA neurons feed directly into...

2009-07-22 07:14:19

Having trouble losing weight and keeping your type 2 diabetes under control? A key enzyme in the brain may be behind the difficulties. A new study shows decreasing the levels of the brain enzyme prolylcarboxypeptidase (PRCP) led to weight loss and a decreased risk of type 2 diabetes. Researchers studied mice and found  PRCP is located in the hypothalamus. PRCP regulates levels of the alpha-melanocyte stimulating hormone alpha-MSH, which is a peptide known for inhibiting food intake and...

2009-07-21 13:54:30

In a major advance in obesity and diabetes research, Yale School of Medicine scientists have found that reducing levels of a key enzyme in the brain decreased appetites and increased energy levels.Reductions in the levels of the enzyme prolylcarboxypeptidase (PRCP) led to weight loss and a decreased risk of type 2 diabetes in mice, according to research published in the August issue of the Journal of Clinical Investigation. The team found that PRCP is located in the hypothalamus and regulates...

2009-07-21 12:39:36

The peptide alpha-MSH works in a region of the brain known as the hypothalamus to suppress appetite. A team of researchers, at Yale University School of Medicine, New Haven, and the University of California Davis, has provided new insight into the way in which levels of the active form of alpha-MSH are regulated in mice. Specifically, genetic and biochemical analysis performed by the team, led by Sabrina Diano and Craig Warden, indicated that the protein PRCP is expressed in the hypothalamus...

2009-07-07 06:15:00

Data published in July 7, 2009 Issue of Proceedings of the National Academy of Sciences QUEBEC CITY, July 7 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today announced publication in the renowned American scientific journal, Proceedings of the National Academy of Sciences (PNAS), of new data supporting the use of AEterna Zentaris' ghrelin receptor antagonist compound, AEZS-123...

2009-06-12 11:12:08

Penn Medicine endocrinologists to present study results at ENDO 2009 Older women suffering from clinical frailty stand to benefit from the first potential medical treatment for the condition, according to a study presented today by Penn Medicine researchers at ENDO, The Endocrine Society's 91st Annual Meeting. Ghrelin, a hormone that stimulates appetite, was administered to older women diagnosed with frailty, a common geriatric syndrome characterized by unintentional weight loss, weakness,...

2009-06-10 09:35:00

Researchers at Imperial College London have identified a new appetite suppressant for promoting weight loss that they say works in rodents and may one day be used to develop an effective anti-obesity treatment. Results of the new study were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.The experimental treatment, prokineticin 2, is a recently discovered signaling molecule that occurs naturally in the part of the brain that helps control hunger. Both lean and...

2009-06-02 14:32:22

 In investigating the complex neurocircuitry behind weight gain and glucose control, scientists have known that the hormone leptin plays a key role in the process. But within the myriad twists and turns of the brain's intricate landscape, the exact pathways that the hormone travels to exert its influence have remained a mystery.Now, a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) sheds further light on the subject. Reported in tomorrow's issue of the journal...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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