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Last updated on April 16, 2014 at 1:21 EDT

Latest Applied genetics Stories

2012-01-04 00:00:00

AMSTERDAM, January 4, 2012 /PRNewswire/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to its gene therapy program for the treatment of hemophilia B. Orphan designation in the U.S. could provide up to seven years market exclusivity on regulatory approval. Orphan designation for AMT's hemophilia program in the European Union was...

2011-12-27 07:00:00

SALT LAKE CITY, Dec. 27, 2011 /PRNewswire/ -- While many Americans are resolving to address financial issues or lose weight in 2012, a new survey shows that some adults are looking to find answers to an important question - who is the child's father? The survey, which was commissioned by Identigene, the largest direct-to-consumer DNA paternity testing laboratory and makers of the Identigene DNA Paternity Test, the only paternity test available at the drug store, reveals that...

2011-12-21 11:43:31

Diabetes is a major risk factor for cardiovascular disease and can reduce blood supply to the heart tissue and damage cardiac cells, resulting in heart failure. New research has investigated if nerve growth factor (NGF) gene therapy can prevent diabetic heart failure and small vascular disease in mice. The study by Professor Costanza Emanueli, British Heart Foundation Senior Research Fellow and colleagues of the Bristol Heart Institute in the Regenerative Medicine Section of the School of...

2011-12-19 05:03:00

FAIRFIELD, Ohio, Dec. 19, 2011 /PRNewswire/ -- DDC (DNA Diagnostics Center), one of the largest DNA testing companies in the world, announced today the acquisition of Orchid Cellmark, Inc.'s (Orchid Cellmark) government paternity business. Orchid Cellmark, a leading international provider of DNA testing services primarily for forensic and family relationship applications, is now a wholly-owned subsidiary of Laboratory Corporation of America® Holdings...

2011-12-13 14:58:05

A recent article in the New England Journal of Medicine showed that Factor IX gene therapy in patients with hemophilia B was able to convert severe hemophilia to moderate or even mild disease. In a timely commentary, Thierry VandenDriessche, PhD, Methods Editor for Human Gene Therapy and Human Gene Therapy Methods says that this clinical trial represents an important milestone and "demonstrates unequivocally that gene therapy can result in a sustained therapeutic effect in hemophilia B...

2011-12-13 06:00:00

RICHMOND, Calif., Dec. 13, 2011 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced the presentation of new data demonstrating the ability to permanently correct a disease gene in an adult mouse model of hemophilia B using systemic delivery of zinc finger nucleases (ZFNs) at the 53nd Annual Meeting of the American Society of Hematology (ASH). "We have demonstrated functional correction of a human gene for the clotting factor, Factor IX, with a single, systemic...

2011-12-07 20:26:06

A groundbreaking study that investigates how genome sequencing can be incorporated into the clinical care of children with cancer will launch at Baylor College of Medicine and Texas Children's Cancer Center with support from a $6 million grant from the National Human Genome Research Institute and the National Cancer Institute. The Clinical Sequencing Exploratory grant from the NHGRI and NCI, which are part of the National Institutes of Health, was awarded to co-investigators Dr. Sharon...

2011-12-01 10:52:46

Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, the investigators found no side effects from using a "chimeric" virus to deliver replacement genes for an essential muscle protein in patients with muscular dystrophy. "This trial demonstrates that gene therapy is no longer limited by the viruses we find in nature, and...

2011-12-01 01:46:31

New research in the FASEB Journal suggests that site-specific recombinases from either yeast or phages act not only to tag and target but also to exchange specific genes in DNA A combination of two techniques promises to improve the efficiency and effectiveness of experimental gene therapies, while also reducing potential side effects says a new research report published in the December 2011 issue of the FASEB Journal (http://www.fasebj.org). The report describes how scientists from...

2011-11-30 15:07:08

University of Oregon's RAD technology opens route to see important genetic markers in rainbow trout Two distinct populations of rainbow trout -- one in Alaska, the other in Idaho -- share a genetic trait that could have huge implications for fisheries conservation and management, an eight-member research team reports. The common trait is a similar rapid rate of development that has allowed these different salmomid subspecies to adapt to their native rivers in Alaska and Idaho. The...