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Latest Aromatase Stories

2014-01-29 04:20:04

Source: Waseda UniversityHopes for a method of reducing aggressive behavior in humansTokyo, Jan 29, 2014 - (ACN Newswire) - A group led by Professor Kazuyoshi Tsutsui and Research Associate Takayoshi Ubuka, of the Waseda University Center for Advanced Biomedical Sciences, has discovered a hormonal mechanism for controlling aggressiveness in male birds.Male aggressiveness has long been thought to depend on androgen, a male sex hormone produced in the testes. However, previous research...

2013-11-04 16:36:10

Gene sequencing reveals mutations in estrogen receptor Researchers at the University of Michigan Comprehensive Cancer Center have identified a type of mutation that develops after breast cancer patients take anti-estrogen therapies. The mutations explain one reason why patients often become resistant to this therapy. The study appears online in Nature Genetics. The discovery stems from a program at the U-M Comprehensive Cancer Center called Mi-ONCOSEQ in which patients with advanced...

2013-07-10 10:10:45

The idea that females are more resilient than males in responding to stress is a popular view, and now University at Buffalo researchers have found a scientific explanation. The paper describing their embargoed study will be published July 9 online, in the high-impact journal, Molecular Psychiatry. "We have examined the molecular mechanism underlying gender-specific effects of stress," says senior author Zhen Yan, PhD, a professor in the Department of Physiology and Biophysics in the UB...

2012-06-11 11:50:29

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment. Researchers at Washington University School of Medicine in St. Louis uncovered mutations linked to whether or not women respond to aromatase inhibitors, drugs often prescribed to shrink large tumors before surgery. These...

2012-06-07 09:14:54

Research suggests selection shapes evolution of aggression via changes in sex steroid molecules An Indiana University biologist has shown that natural variation in measures of the brain's ability to process steroid hormones predicts functional variation in aggressive behavior. The new work led by Kimberly A. Rosvall, a postdoctoral fellow and assistant research scientist in the IU Bloomington College of Arts and Sciences' Department of Biology, has found strong and significant...

2012-03-24 03:36:40

Treatment with aromatase inhibitors enables some women to have lumpectomy Preoperative treatment with aromatase inhibitors increases the likelihood that postmenopausal women with estrogen receptor-positive breast cancer will be able to have breast-conserving surgery rather than a mastectomy, according to the results of a national clinical trial presented today at the Society of Surgical Oncology annual meeting in Orlando, Fla. "We found that half of the postmenopausal women in the study...

2012-01-19 13:34:16

Aromatase inhibitors (AIs) prevent the conversion of androgens to estrogens, and could play a role in the development of breast cancer. This study of 36 pre-menopausal women consisted of a cross-over intervention trial to determine if there were differences between red wine and white wine in their effects on AIs. Subjects sequentially consumed eight ounces of red wine, followed by white wine (or vice versa), each beverage for a one-month period. The investigators concluded that red wine, but...

2012-01-11 06:37:05

(Ivanhoe News Wire) -- A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study. "Antiestrogens have been shown to prevent breast cancer in some women," Jill M. Siegfried, Ph.D., professor in the department of pharmacology and chemical biology at University of Pittsburgh Cancer Institute, was quoted as saying. "If antiestrogens can prevent lung cancer as well,...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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