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Latest Artemisinin Stories

Drug-Resistant Malaria Spreading, Say Experts
2012-04-08 06:03:37

Scientists have expressed concerns that resistance to the primary treatment for malaria is increasing, potentially putting thousands of additional people at risk of losing their lives to the disease, according to various media reports. According to Brendan Trembath of ABC News Australia, lead researchers Francois Nosten, a researcher at the Shoklo Malaria Research Unit in Thailand, and colleagues reported that they had discovered drug-resistant strains of the Plasmodium falciparum parasite...

2012-04-05 21:19:01

Genetics study identifies key genome region underlying artemisinin resistance in malaria parasite Evidence that the most deadly species of malaria parasite, Plasmodium falciparum, is becoming resistant to the front line treatment for malaria on the border of Thailand and Myanmar (Burma) is reported in The Lancet today. This increases concern that resistance could now spread to India and then Africa as resistance to other antimalarial drugs has done before. Eliminating malaria might then...

2012-04-05 21:17:39

Emergence of resistance to the drug artemisinin in western Thailand has created a critical point in global efforts to control and eliminate malaria worldwide, according to a new study published in the Lancet, a British Medical Journal, by researchers at the Texas Biomedical Research Institute and their collaborators in Thailand. A second study, published concurrently in the journal Science by the same research groups, identifies a major region of the malaria parasite genome associated with...

2012-02-28 21:51:51

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations with no observed toxicity to the mouse. The researchers found the drug by screening a library of about 1,000 compounds used in previous efforts to target an important...

2012-02-22 10:21:54

In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei, and Plasmodium yoelii. These results provide a valuable guide to help researchers decide which drugs and compounds show most promise as potential future antimalarial drugs for blocking the...

2012-01-17 22:35:12

In future it should be possible to produce the best anti-malaria drug, artemisinin, more economically and in sufficient volumes for all patients The most effective anti-malaria drug can now be produced inexpensively and in large quantities. This means that it will be possible to provide medication for the 225 million malaria patients in developing countries at an affordable price. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie...

2011-12-13 14:51:49

The largest ever study to assess the effects of malaria and its treatment in the first trimester of pregnancy has shown that the disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk. In the study, carried out at the Shoklo Malaria Research Unit (SMRU), in Thailand and funded by the Wellcome Trust, researchers examined medical records of women attending the unit's antenatal clinic over the 25 years since...

Breakthrough In The Battle Against Malaria
2011-11-30 05:54:45

Study identifies new ways to kill the human malaria parasite, Plasmodium falciparum An international team of scientists has announced a breakthrough in the fight against malaria, paving the way for the development of new drugs to treat the deadly disease. According to the World Health Organisation malaria currently infects more than 225 million people worldwide and accounts for nearly 800,000 deaths per year. Most deaths occur among children living in Africa where a child dies every 45...

2011-11-09 10:05:25

For some time now, artemisinin, derived from a Chinese herb, has been the most powerful treatment available against malaria. To avoid the malaria parasite becoming resistant, the World Health Organisation (WHO) strongly recommends combining artemisinin with another anti-malarial drug. But there are different formulations and derivatives, in different combinations and with dosing schemes. Scientists from the Institute of Tropical Medicine (ITM) carried out a head-to-head comparison of four...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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