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2011-06-22 07:33:30

(Ivanhoe Newswire) -- Brain cancer patients who are able to exercise live significantly longer than sedentary patients, according to this study. "This provides some initial evidence that we need to look at the effects of exercise interventions, not only to ease symptoms but also to impact progression and survival," Lee W. Jones, PhD, associate professor in the Duke Cancer Institute and senior author of the study, was quoted as saying. The study enrolled 243 patients at the Preston Robert...

2011-06-06 00:30:00

CHICAGO, June 6, 2011 /PRNewswire/ -- Cell Therapeutics, Inc. ("CTI") (NASDAQ: CTICD and MTA: CTIC) announced encouraging interim results of a phase II clinical study of OPAXIO (paclitaxel poliglumex, PPX) combined with temozolomide ("TMZ") and radiotherapy ("RT") in patients with newly diagnosed high-grade malignant brain tumors (astrocytomas and glioblastomas). While not a randomized trial, treatment with OPAXIO, TMZ and RT resulted in a median progression free survival (PFS) of 13.5...

2011-04-11 15:59:12

Early research shows synthetic hypericin to be well-tolerated as a salvage therapy for malignant gliomas Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online on March 31, 2011 in the journal Cancer. Malignant gliomas, tumors that arise in the brain or spine, are largely incurable cancers with a poor prognosis. An...

2011-04-07 09:00:00

SARASOTA, Fla., April 7, 2011 /PRNewswire/ -- Linda Roberts was puzzled when her favorite food, chocolate ice cream, suddenly did not taste good, and her prized orchids didn't smell nice either. When she began having sudden, severe headaches, she mentioned the changes in taste and smell to her doctor. After several tests, Roberts was diagnosed with a glioblastoma multiforme, the most aggressive form of brain tumor. As frightening as the diagnosis was, Roberts took the time to research...

2011-03-15 15:28:27

Pilocytic astrocytoma, the most common brain tumor in children, is usually slow-growing and benign. However, surgeons often cannot completely remove the diffusely growing tumor. This means that patients need further treatment in order to destroy remaining tumor tissue. Chemotherapy or radiation therapy can lead to severe side-effects and have only little effect on these slowly growing tumors. Affected children therefore urgently need new, targeted therapies. A typical genetic defect in these...

2011-03-14 16:16:58

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor, and there are few medical therapies available to those patients for whom surgery is not curative. However, it has been difficult to design targeted PA therapies because the cellular mechanisms that lead to the cancer are incompletely understood, and there is no animal model of the disease. Recent work has suggested that activation of a particular cell signaling pathway may be required for PA formation, and mutations in one...

2011-03-10 13:24:52

A detailed analysis of gene fusions present at high frequency in the most common pediatric brain tumors has been performed for the first time in a study published online today in Genome Research (www.genome.org), shedding new light on how these genomic rearrangements form in the early stages of cancer. Genomic rearrangements, genetic changes that alter the structure of chromosomes, have a positive role in evolution by creating genetic diversity and new genes; however, rearrangements can also...

2010-12-14 23:50:19

For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer.  A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.  This distinction explains why oligodendroglioma is more responsive to therapy than other brain tumors such as glioblastoma multiforme. The finding is significant, the researchers say,...

2010-02-18 15:03:00

PITTSBURGH, Feb. 18 /PRNewswire-USNewswire/ -- Neurosurgeons at Allegheny General Hospital (AGH) are exploring use of a drug that illuminates brain tumor cells to determine if the experimental visualization technique will enhance their ability to surgically excise tumors and improve patient survival. AGH is one of just three medical centers in the country approved by the U.S. Food and Drug Administration to investigate the efficacy of an oral fluorescent compound, called 5-aminoevulnic...

2010-02-11 08:25:00

TUSTIN, Calif., Feb. 11 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM) today reported publication of data in the online edition of the journal Current Cancer Therapy Reviews that supports the clinical potential of the company's novel brain cancer agent Cotara® for the treatment of patients with glioblastoma multiforme (GBM), the deadliest form of brain cancer.(1) Cotara specifically targets cells at the center of brain tumors, so its...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'