Latest Ataluren Stories
A drug developed to treat genetic diseases such as Duchenne muscular dystrophy and cystic fibrosis may need a radical rethink. In a new study published on 25 June in the open access journal PLOS Biology, researchers question the mechanistic basis of the drug called PTC124 (also known as Ataluren), casting doubt as to whether it has the molecular effects that are claimed for it. This may have implications for its effectiveness in treating genetic diseases. An estimated 10% of all human...
Biologists at Mainz University achieve repair and read-through of stop mutations responsible for the disease After years of basic research, scientists at Johannes Gutenberg University Mainz (JGU) are increasingly able to understand the mechanisms underlying the human Usher syndrome and are coming ever closer to finding a successful treatment approach. The scientists in the Usher research group of Professor Dr. Uwe Wolfrum are evaluating two different strategies. These involve either the...
- Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
- Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
- Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
- A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.