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Latest Atheroma Stories

2010-05-14 09:49:28

Finding could lead to the development of new treatments for atherosclerosis Researchers at two laboratories at NYU Langone Medical Center have collaborated to identify a tiny micro-RNA, miR-33, that regulates key genes involved in cellular cholesterol transport. The study, published online May 13, 2010 in Science, found that inhibitors of miR-33 may be beneficial because they could enhance cholesterol removal from tissues and raise levels of HDL -- shown in clinical trials to promote...

2010-05-06 14:15:00

A new study by researchers at the Swedish medical university Karolinska Institutet shows that the immune defense's T cells can attack the "bad" LDL cholesterol and thereby cause an inflammation that leads to atherosclerosis. By producing a vaccine against the T cell receptors, the researchers have managed to inhibit the development of atherosclerosis in animals. The study is presented online in the distinguished periodical Journal of Experimental Medicine and is expected to be of considerable...

2010-04-29 08:29:52

Cholesterol crystals lead to life-threatening inflammation in blood vessel walls In addition to crystallized cholesterol, atherosclerotic plaques always contain large quantities of immune cells but, surprisingly, no bacteria or viruses. It was previously unclear just how the body's own defense forces are called into action. Even animals that are kept in an absolutely sterile environment can suffer from "clogging" or "furring" of the arteries when their food contains high levels of...

2010-04-09 14:00:00

TSX Exchange Symbol: RVX SAN FRANCISCO and CALGARY, April 9 /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that key scientific data was communicated in an oral presentation highlighting the novel features of RVX-208, the Company's lead drug, during the Atherosclerosis, Thrombosis, Vascular Biology (ATVB) conference being held in San Francisco, California. The presentation titled "RVX-208, an Orally Active Small Molecule, Raises ApoA-I...

2010-02-28 08:53:07

Two stroke-prevention procedures are safe and equally beneficial for men and women at risk for stroke, but the effectiveness does vary by age, say researchers at the University of Alabama at Birmingham (UAB) in collaboration with other North American stroke investigators. In findings reported Feb. 26 at the International Stroke Conference in San Antonio, Texas, the researchers say physicians now have better information when tailoring their treatment plans for patients at risk for stroke. The...

2010-02-25 13:00:00

Cleveland Clinic coordinates IVUS testing of RVX-208 in acute coronary syndrome patients CALGARY, Feb. 25 /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that it has officially activated the first site for the ASSURE 1 trial and commenced enrollment of patients for dosing of RVX-208. ASSURE 1 is the second Resverlogix Phase 2 clinical trial, led by Cleveland Clinic. This trial will examine RVX-208, Resverlogix's oral small molecule...

2010-01-07 18:50:03

Inflammation, other immune-system factors may increase cardiovascular risk A Massachusetts General Hospital (MGH) study has found that relatively young men with longstanding HIV infection and minimal cardiac risk factors had significantly more coronary atherosclerotic plaques "“ some involving serious arterial blockage "“ than did uninfected men with similar cardiovascular risk. The investigation appearing in the January 2010 issue of the journal AIDS is the first to use CT...

2009-12-04 10:04:05

By measuring the total gene activity in organs relevant for coronary artery disease (CAD), scientists at the Swedish medical university Karolinska Institutet have identified a module of genes that is important for the recruitment of white blood cells into the atherosclerotic plaque. The findings, which are to be published in the open-access journal PLoS Genetics, suggest that targeting the migration of white blood cells in the development of atherosclerosis may help to reduce the risk for...

2009-11-20 21:05:00

BEVERLY HILLS, Calif., Nov. 20 /PRNewswire/ -- In the study presented today at the American Heart Association Scientific Sessions in Orlando, Florida today, The Effect of Extended-release Niacin or Ezetimibe Added to Chronic Statin Therapy On Carotid Intima Media Thickness (ARBITER 6-HALTS), study found that: Adding the cholesterol drug niacin to a statin improved HDL ("good") cholesterol levels and significantly reduced carotid arterial plaque buildup measured with ultrasound within 8...

2009-11-18 14:50:57

Blood cholesterol levels improved, but arteries do not show it The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows. In tests on 145 Baltimore-area men and women with existing atherosclerosis,...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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