Latest ATP-binding cassette transporter Stories
BANGALORE, India, June 9, 2014 /PRNewswire/ -- Clinigene International Ltd, a subsidiary of Syngene International Ltd, India's leading Contract Research Services provider,
Scientists at the Max Planck Institute for Chemical Ecology in Jena, Germany, have discovered the decisive biological stimulator for the accumulation of defensive substances in leaf beetle larvae used by the insects to fend off predators: ABC transport proteins, which are found in large quantities in glandular cells of the larvae.
Researchers have tried for decades to understand the undulations and gyrations that allow transport proteins to shuttle molecules from one side of a cell membrane to the other. Now scientists report that they have found a way to penetrate the mystery.
University of Toronto researchers are helping demystify an important class of proteins associated with disease, a discovery that could lead to better treatments for cancer, cystic fibrosis and many other conditions.
For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells.
A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future.
How a transport protein obtains its driving force from the energy storage molecule ATP, has been tracked dynamically by RUB researchers.
ABC transporters are membrane proteins that actively pump a wealth of molecules across the membrane.
Scientists at IRB Barcelona resolve a three-dimensional structure required for the function of some vital cell transporters which communicate cells with the external environment.
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