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Latest Atrophy Stories

2011-03-11 00:00:27

Approximately 50,000 Americans suffer from multiple system atrophy. A strong need exists for more awareness and education regarding diagnosis and management of this rare disease. Currently there is no cure or effective way to slow the progression of MSA and funding for more research is desperately required. Anywhere, U.S. (PRWEB) March 10, 2011 "” There are no Hollywood celebrities linked to MSA (Multiple System Atrophy)"”just more than 2,300 fans known on Facebook as "Miracles...

2010-12-15 06:00:00

WALTHAM, Mass., Dec. 15, 2010 /PRNewswire/ -- Repligen Corporation (Nasdaq: RGEN) today announced that the Company has received $1,400,000 in research funding from the Muscular Dystrophy Association ("MDA") to support the ongoing development of RG3039 for Spinal Muscular Atrophy ("SMA"). RG3039, our lead compound, is an inhibitor of an RNA processing enzyme which targets increased production of SMN, a protein of deficient levels in patients with SMA. The goal of this grant is to support...

2010-12-02 21:34:47

Botulinum toxin A creates muscle weakness and atrophy following long term use A new study by researchers at the Faculty of Kinesiology, University of Calgary, is raising questions about the therapeutic use of botulinum toxin A. The study found that animals injected with Clostridium Botulinum type A neurotoxin complex (BOTOX, Allergan, Inc., Toronto, Ontario, Canada) experienced muscle weakness in muscles throughout the body, even though they were far removed from the injection site. The study...

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2010-03-22 08:47:58

A new study in the Journal of Cell Biology (JCB) identifies a cytokine signaling pathway that induces the breakdown of disused skeletal muscle. Blocking this pathway could prevent immobilized patients from losing their muscle tissue. The article appears in the March 22 issue of the JCB. Skeletal muscle wastes away when its activity is reduced by, for example, a spinal cord injury. Although the mechanism by which muscle fibers break down is understood fairly well, how the process is triggered...

2010-03-02 07:30:00

OSAKA, Japan, ATLANTA and ANN ARBOR, Mich., March 2 /PRNewswire/ -- Shionogi & Co., Ltd. and QuatRx Pharmaceuticals Company, a privately-held pharmaceutical company, today announced that they have entered into a worldwide license agreement to develop and market ospemifene, a selective estrogen receptor modulator ("SERM"). Under the terms of this agreement, Shionogi will have worldwide marketing rights to ospemifene. QuatRx will receive an up-front payment of $25 million and is eligible...

2010-03-01 07:48:29

Reversing a protein deficiency through gene therapy can correct motor function, restore nerve signals and improve survival in mice that serve as a model for the lethal childhood disorder spinal muscular atrophy, new research shows. This muscle-wasting disease results when a child's motor neurons "“ nerve cells that send signals from the spinal cord to muscles "“ produce insufficient amounts of what is called survival motor neuron protein, or SMN. This reduced protein in motor...

2010-01-04 15:22:50

New research in the FASEB Journal shows free radicals damage mitochondria in our muscle cells, resulting in age-related muscle loss If you're an aging baby boomer hoping for a buffer physique, there's hope. A team of American scientists from Texas and Michigan have made a significant discovery about the cause of age-related muscle atrophy that could lead to new drugs to halt this natural process. This research, available online the FASEB Journal (http://www.fasebj.org), shows that free...

2009-12-10 14:00:53

Findings could lead to novel therapeutic intervention strategies for neuromuscular disorders; data published in latest issue of Science  miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA-based therapeutics for cardiovascular and muscle disease, today announced the publication of data demonstrating that microRNA-206 (miR-206) plays a crucial role in the progression of amyotrophic lateral sclerosis (ALS or Lou...

2009-12-01 14:29:14

In order to maintain muscle strength with age, cells must rid themselves of the garbage that accumulates in them over time, just as it does in any household, according to a new study in the December issue of Cell Metabolism, a Cell Press journal. In the case of cells, that waste material includes spent organelles, toxic clumps of proteins, and pathogens. The researchers made their discovery by studying mice that were deficient for a gene required for the tightly controlled process of...

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2009-10-01 06:14:41

A study led by researchers at the University of California, Berkeley, has identified critical biochemical pathways linked to the aging of human muscle. By manipulating these pathways, the researchers were able to turn back the clock on old human muscle, restoring its ability to repair and rebuild itself. The findings were reported in the Sept. 30 issue of the journal EMBO Molecular Medicine, a peer-reviewed, scientific publication of the European Molecular Biology Organization. "Our study...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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