Latest Atypical teratoid rhabdoid tumor Stories
Medulloblastoma is the most common malignant brain tumor in children. Disseminated medulloblastoma is particularly lethal and requires extensive radiation therapy to the brain, which can cause brain damage. An oncolytic measles virus has shown effectiveness in a new model of disseminated human medulloblastoma. A strain of measles virus engineered to kill cancer cells prolongs survival in a model of medulloblastoma that is disseminated in the fluid around the brain,...
Washington University Pediatric Cancer Genome Project provides first evidence linking cancer to mutations in genes involved in DNA organization Researchers studying a rare, lethal childhood tumor of the brainstem discovered that nearly 80 percent of the tumors have mutations in genes not previously tied to cancer. Early evidence suggests the alterations play a unique role in other aggressive pediatric brain tumors as well. The findings from the St. Jude Children's Research Hospital –...
St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project provides first evidence linking cancer to mutations in genes involved in DNA organization MEMPHIS, Tenn., Jan. 29, 2012 /PRNewswire-USNewswire/ -- Researchers studying a rare, lethal childhood tumor of the brainstem discovered that nearly 80 percent of the tumors have mutations in genes not previously tied to cancer. Early evidence suggests the alterations play a unique role in other...
Bright color distinguishes tumor from healthy tissue to improve tumor resection Just 24 hours after Lisa Rek sang at her niece's wedding, her husband Brad was driving her to a local hospital. "The pain got worse. When we got to the emergency room, I said to Brad 'something is just not right,'" Rek remembers. After an MRI showed a suspected tumor, Rek was immediately flown to Seidman Cancer Center at University Hospitals (UH) Case Medical Center, where Andrew Sloan, MD, diagnosed her...
CLEVELAND, Dec. 1, 2011 /PRNewswire/ -- Just 24 hours after Lisa Rek sang at her niece's wedding, her husband Brad was driving her to a local hospital. "The pain got worse. When we got to the emergency room, I said to Brad 'something is just not right,'" Rek remembers. After an MRI showed a suspected tumor, Rek was immediately flown to Seidman Cancer Center at University Hospitals (UH) Case Medical Center, where Andrew Sloan, MD, diagnosed her with Stage 4 glioblastoma, the...
Study led by St. Jude Children’s Research Hospital scientists points to possible new treatment targets for diffuse intrinsic pontine gliomas; may tip the scales in the current debate about tumor biopsies The largest study ever of a rare childhood brain tumor found more than half the tumors carried extra copies of specific genes linked to cancer growth, according to research led by St. Jude Children's Research Hospital investigators. The findings identify possible new targets for...
Study led by St. Jude Children's Research Hospital scientists points to possible new treatment targets for diffuse intrinsic pontine gliomas; may tip the scales in the current debate about tumor biopsies MEMPHIS, Tenn., Sept. 19, 2011 /PRNewswire-USNewswire/ -- The largest study ever of a rare childhood brain tumor found more than half the tumors carried extra copies of specific genes linked to cancer growth, according to research led by St. Jude Children's Research Hospital investigators....
St. Jude Children's Research Hospital scientists lead research that settles a century-old debate about retinoblastoma's beginnings and identify new targets for treating the childhood eye tumor MEMPHIS, Tenn., Aug. 15, 2011 /PRNewswire-USNewswire/ -- A research team led by St. Jude Children's Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma. Their work also settles a scientific debate by showing the cancer's cellular...
(Ivanhoe Newswire) "“ The largest study yet of adult childhood cancer survivors found that the first cancer is just the beginning of a lifelong battle against different forms of the disease for about 10 percent of these survivors.The study involved 14,358 individuals and was led by St. Jude Children's Research Hospital. Investigators leading the effort reported that 1,382, or 9.6 percent, of survivors developed new tumors unrelated to their original cancers. About 30 percent of those...
Comprehensive study of medulloblastoma suggests targeted drugs may be especially effective in childrenPediatric cancer researchers at The Children's Hospital of Philadelphia contributed important expertise to a new landmark study of medulloblastoma, a type of brain tumor typically found in children. The large multicenter study defines the genetic landscape of this cancer, and holds intriguing clues to gene changes on signaling pathways that may become fruitful targets for future therapies.The...
