Latest Atypical teratoid rhabdoid tumor Stories

Comprehensive study of medulloblastoma suggests targeted drugs may be especially effective in childrenPediatric cancer researchers at The Children's Hospital of Philadelphia contributed important expertise to a new landmark study of medulloblastoma, a type of brain tumor typically found in children. The large multicenter study defines the genetic landscape of this cancer, and holds intriguing clues to gene changes on signaling pathways that may become fruitful targets for future therapies.The...

International effort led by St. Jude Children's Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancersInvestigators have demonstrated for the first time that the most common malignant childhood brain tumor, medulloblastoma, is actually several different diseases, each arising from distinct cells destined to become different structures. The breakthrough is expected to...

Accurate data critical to early diagnosis, treatment Montreal, Canada (Vocus) November 18, 2010 An abstract of the study, "A step towards determining the annual incidence of metastatic brain tumors in the United States," to be presented on Friday, Nov. 19, 2010 at the Society for Neuro-Oncology (SNO) 2010 Annual Meeting, questions the actual incidence of newly diagnosed metastatic brain tumors and supports much lower estimates. Funded by the American Brain Tumor Association and...

By Jim Dryden, Washington University in St. LouisResearchers at Washington University School of Medicine in St. Louis have identified a gene linked to the spread of eye melanoma.Although more research is needed, the researchers say the discovery is an important step in understanding why some tumors spread (metastasize) and others don't. They believe the findings could lead to more effective treatments.Reporting online in the journal Science Express, the team found mutations in a gene called...

Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor. The research focused on a new way to attack the tumors by blocking the Hedgehog pathway that is linked to approximately 20 percent of medulloblastomas.The study is the first to report that the drug can be...

CHICAGO, June 5 /PRNewswire/ -- Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented today at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor. The research focused on a new way to attack the tumors by blocking the Hedgehog pathway that is linked to approximately 20 percent of medulloblastomas. The study is the...

ROCKVILLE, Md., May 25 /PRNewswire/ -- A teen diagnosed with an inoperable brain tumor and determined to raise awareness for the disease will be undertaking an even greater challenge in response to recent findings by the Central Brain Tumor Registry of the United States (CBTRUS). Justin Friedlander, a 13-year-old basketball enthusiast, is aiming to shoot a basket for each person who will be diagnosed with a primary brain tumor in the United States this year. Friedlander originally planned...

Study led by St. Jude Children's Research Hospital investigators underscores the need to better understand the genetic missteps that give rise to about 20 percent of childhood brain tumors MEMPHIS, Tenn., May 17 /PRNewswire-USNewswire/ -- The most comprehensive analysis yet of the genetic imbalances at the heart of childhood brain tumors known as high-grade gliomas (HGGs) identified a cancer gene that is unusually active in some tumors and is now the focus of a St. Jude Children's Research...

CLEARWATER, Fla., May 4 /PRNewswire-USNewswire/ -- Each day in the United States, 482 people are diagnosed with a brain tumor. For these 482 people, not many treatments exist. With the current treatments available, only 5% of those diagnosed with a Glioblastoma Multiform will survive more than 5 years. Only two new treatments have been approved by the FDA in the past two decades. Hope is on the horizon: there are a few promising treatments that exist in the clinical trial stages....

WASHINGTON, April 21 /PRNewswire/ -- Certified Platinum recording artist and American Idol® winner David Cook is lacing up for a very personal cause on Sunday, May 2 as he joins walkers, runners, activists and survivors at the 13th Annual Race for Hope - DC, presented by Cassidy Turley (www.curebraintumors.org). Cook has spoken on numerous occasions about his brother, Adam, who lost his valiant battle with brain cancer last year. This year, Cook returns to the Race for Hope - DC to...