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Latest Autoantibody Stories

2011-06-02 22:28:53

Researchers from Harvard Medical School and MIT have developed a new approach for identifying the "self" proteins targeted in autoimmune diseases such as multiple sclerosis, diabetes and rheumatoid arthritis. In a paper published in Nature Biotechnology, H. Benjamin Larman and colleagues showed that errant immune responses which mistakenly target the body's own proteins rather than foreign invaders can now be examined in molecular detail. Further research could lead to new insights into the...

2011-05-12 07:00:00

DENVER, May 12, 2011 /PRNewswire/ -- Oncimmune® LLC , maker of EarlyCDT(TM)-Lung, a simple blood test that aids physicians in the risk assessment and early detection of lung cancer, today announced that four poster presentations during the American Thoracic Society's (ATS) International Conference May 13 - 18 in Denver will collectively highlight the diagnostic and economic benefits of EarlyCDT-Lung. Oncimmune's EarlyCDT-Lung test uses a panel of tumor antigens to detect...

2011-04-25 14:18:56

Findings could lead to better diagnostics and more personalized treatment Researchers from Boston University School of Medicine (BUSM) have discovered that human proteins with an affinity for Dermatan Sulfate (DS) have the propensity to become autoantigens. In a companion article, the researchers also found that DS physically interacts with dead cells and that the resulting DS"“autoantigen complexes drive autoreactive B-1a cell responses and autoantibody production both in-vitro and in...

2011-04-15 08:30:00

BOSTON, April 15, 2011 /PRNewswire-USNewswire/ -- In the first study investigating the origins of a little-known condition called chronic ulcerative stomatitis (CUS), researchers at Tufts University School of Dental Medicine provide evidence that an autoimmune response contributes to the painful oral sores that characterize the disease. The study findings support the classification of CUS as a new autoimmune disease. Chronic ulcerative stomatitis is characterized by painful, recurring...

2011-03-10 14:23:13

The long path to Benlysta emphasizes importance of basic research Scientific advances at The Scripps Research Institute were key to laying the foundation for the new drug Benlysta® (belimumab), approved today by the U.S. Food and Drug Administration. Benlysta®, which treats the most common type of lupus, is the first in a new class of pharmaceuticals that prevents the body from attacking its own critical tissues. "I am deeply gratified that our scientific...

2011-02-04 01:04:17

Researchers at Dana-Farber Cancer Institute in Cambridge, Mass., in collaboration with Jackson Laboratory scientists, have identified a regulatory defect that drives lupus. Correcting the defect "may represent an effective therapeutic approach to systemic lupus erythematosus-like autoimmune disease," the researchers state in their research paper, published in the Proceedings of the National Academy of Sciences. The research team was led by Harvey Cantor, M.D., chair of the department of...

2011-01-04 14:10:00

New research finds pattern for detecting 'false-positive' ANA results The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to detect ANA. However, studies have shown that a "false-positive" ANA test occurs in up to 13% of healthy individuals. In such cases the test detects the presence of autoantibodies that apparently are not associated with...

2010-12-31 12:20:16

(Ivanhoe Newswire) "“ A new study provides insight into the underlying pathology associated with the autoimmune disease, systemic lupus erythematosus (SLE). The research shows an unexpected role for a key type of immune cell could provide a potential new therapeutic strategy for SLE and, possibly, other autoimmune diseases. SLE is a chronic systemic disease that can affect many regions of the body and, as a result, presents with diverse clinical symptoms. As is characteristic of other...

2010-12-17 12:53:03

A new study provides fascinating insight into the underlying pathology associated with the autoimmune disease, systemic lupus erythematosus A new study provides fascinating insight into the underlying pathology associated with the autoimmune disease, systemic lupus erythematosus (SLE). The research, published by Cell Press in the December issue of the journal Immunity, reveals an unexpected role for a key type of immune cell and provides a potential new therapeutic strategy for SLE and,...

2010-11-25 08:17:35

(Ivanhoe Newswire) -- Chronic obstructive pulmonary disease (COPD), in its moderate or severe form - may be an auto-immune issue, according to a new study. Researchers in Spain studied the presence of auto-antibodies in patients with COPD and compared them to levels of control subjects. They found that a significant number of patients with COPD had significant levels of auto-antibodies circulating in their blood, about 5-10 times the level in the controls. "We showed that between one third...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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