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Latest Autoantigens Stories

Malaria Pathogen's Cellular Skeleton Under A Super-microscope
2014-04-18 13:17:53

Helmholtz Centre for Infection Research This news release is available in German. The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different versions of this protein in the parasite in high detail. Their results, published in the scientific journal...

2012-06-11 19:54:23

An actin-ratchet tightens the contractile ring that severs budding daughter cells from their yeast mothers During the final stage of cell division, a short-lived contractile ring constricts the cellular membrane and eventually separates the dividing cell in two. Although this "molecular muscle's" composition, mainly actin and myosin, is similar to its skeletal counterpart, the force-producing mechanism is fundamentally different, report researchers at the Stowers Institute for Medical...

2011-12-15 17:08:35

A generally accepted 44-year-old assumption about how certain kinds of bacteria make energy and synthesize cell materials has been shown to be incorrect by a team of scientists led by Donald Bryant, the Ernest C. Pollard Professor of Biotechnology at Penn State University and a research professor in the Department of Chemistry and Biochemistry at Montana State University. The research, which will be published in the journal Science on 16 December 2011, is expected to help scientists discover...

2011-10-07 05:48:29

(Ivanhoe Newswire) -- Malfunctioning machines can cause a slew of problems, but when those machines are cells and genes, the result is often cancer.  Scientists have identified a new protein that is crucial to the cell's response to dietary amino acids. One particular piece of cellular machinery known to malfunction in a number of cancers is a group of proteins called mTORC1. This group is like a master control center coordinating many cellular functions by sensing external signals,...

2011-10-06 12:40:41

Sanford-Burnham scientists identify a crucial new component of the machinery cells use to sense dietary amino acids–a mechanism that malfunctions in cancer In cancer, genes turn on and off at the wrong times, proteins aren't folded properly, and cellular growth and proliferation get out of control. Even a cancer cell's metabolism goes haywire, as it loses the ability to appropriately sense nutrients and use them to generate energy. One particular piece of cellular machinery that is...

2011-09-15 05:13:46

(Ivanhoe Newswire) -- A new tool allows scientists to see the immune system like never before. The device, a stimulated emission depletion (STED) microscope, provides sharp images at extremely small scales. It shows how granules from natural killer cells pass through openings in dynamic cell structures to destroy tumor cells and cells infected by viruses. "This new technology enables researchers to see individual elements previously below the physical limits of imaging using light,"...

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2010-03-16 14:06:51

Understanding the steps to the intricate dance inside a cell is essential to one day choreographing the show. By studying the molecules that give a cell its structure, University of Illinois researchers are moving closer to understanding one of those steps: the conga line. Led by Steve Granick, Founder Professor of Engineering and professor of materials science and engineering, of chemistry,  of chemical and biomolecular engineering, and of physics at the U. of I., the team will publish...

2009-12-17 16:57:01

University of Oregon-made technique is putting new light on machinery driving intracellular transport Using new technology developed in his University of Oregon lab, chemist Andrew H. Marcus and his doctoral student Eric N. Senning have captured what they describe as well-orchestrated, actin-driven, mitochondrial movement within a single cell. That movement -- documented in a paper appearing online the week of Dec. 14-18 ahead of regular publication in the Proceedings of the National Academy...

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2008-12-09 10:19:28

Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have identified a key step required for cell division in a study that could help improve therapies to treat cancer. Their work describing the mechanism of the contractile ring "“ a structure that pinches the mother cell into two daughter cells "“ has been published in the December 5 issue of the journal Science. The division of one cell into two is accomplished...

2005-08-31 17:46:43

Several neurologically based afflictions, such as Huntington's, Parkinson's, and Alzheimer diseases, have been correlated to a higher than normal presence of a specific type of enzymes, called transglutaminases (TGase) in the human body. TGases, whose function is to catalyze covalent bonds among proteins, are commonly found in several different human tissues. In the presence of unusually high levels of these enzymes, some proteins tend to form denser clusters than normal in vivo. If the...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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