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Last updated on April 17, 2014 at 21:23 EDT

Latest Autoimmunity Stories

2012-04-09 13:29:21

Insulin is required for the regulation of blood sugar levels. In type I diabetes, the cells that produce insulin are destroyed by the immune system. Chantal Mathieu and colleagues at the University of Leuven have attempted to circumvent this response by taking advantage of the fact that the immune system accepts foreign gut bacteria. The Mathieu group engineered gut bacteria so that they produce a form of insulin, and asked if these bacteria could retrain the immune system in mice with type I...

2012-04-09 09:41:52

Largest Genome-Wide Association Study to Date on Hypothyroidism Conducted Includes Genetic Associations Common to Autoimmune Diseases Using its unique online research platform, 23andMe, a leading personal genetics company, has found five significant genetic associations for hypothyroidism in the largest known genome-wide association study of hypothyroidism conducted to date. The details of the study are now available online in the journal PLoS ONE. “With nearly 90 percent of our...

2012-04-02 20:41:17

The characterisation of a rare immune cell´s involvement in antibody production and ability to ℠remember´ infectious agents could help to improve vaccination and lead to new treatments for immune disorders, say researchers from the Walter and Eliza Hall Institute. The cells, called T follicular helper cells, represent less than half of one per cent of all immune cells, but play a critical role in antibody production and developing long-lasting immunity. However, the cells...

2012-04-02 15:27:35

New research shows it may be no accident when doctors observe how patients suffering from both breast cancer and arthritis seem to have more aggressive cancer. However, the new-found interaction between the two diseases may also suggest a possible treatment. A potential relationship between metastatic breast cancer and autoimmune arthritis, as suggested by past epidemiological studies, has led researchers from the University of North Carolina at Charlotte to perform a series of mouse model...

2012-04-02 09:24:24

New research in the FASEB Journal suggests that a lipid pathway (15-lipoxygenase-Lipoxin A4) is less active in females because estrogen reduces the activity and expression of this pathway Estrogen causes wounds in women to heal slower than in men - who have lower levels of estrogen - says a new study published in the April 2012 issue of the FASEB Journal. In the report, scientists from the University of California, Berkeley, provide the first evidence that mild injury response in the eye...

2012-03-29 22:20:31

Three newly confirmed lupus genes are opening new avenues of research at the Oklahoma Medical Research Foundation. A paper published in the April 6 issue of the American Journal of Human Genetics describes three lupus genes discovered by OMRF researchers as part of a massive international collaboration. With help from partners around the world, including universities and research facilities in Granada, Spain, Taipei, Taiwan, Seoul, Korea, Bogota, Colombia, and across the U.S., OMRF...

2012-03-29 02:26:09

SOUTH SAN FRANCISCO, Calif., March 29, 2012 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the publication of an article in Cell, describing the crystal structures of two forms of the proteasome found in mammalian cells: the constitutive proteasome, expressed by the majority of cells in the body, and the immunoproteasome, expressed in cells derived from the bone marrow, including T-cells and B-cells, two types of white blood cells. In addition, this work includes...

2012-03-23 09:41:10

Study provides important clue in type 1 diabetes; could help scientists identify and validate potential drug targets to alleviate ER stress and preserve beta cell mass in T1D In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, JDRF-funded scientists from the Indiana University School of Medicine have found that a specific type of cellular stress takes place in pancreatic beta cells before the onset of...

2012-03-21 10:24:19

WASHINGTON, March 21, 2012 /PRNewswire/ -- The Lupus Research Institute Coalition of patient advocacy groups throughout the country were out in force on Capitol Hill yesterday to bring critical issues affecting the 1.5 million lupus patients nationwide to the attention of Congressional leaders. Stressing the need for increased public and professional education on lupus was validated by findings of a new survey released Tuesday showing a communication gap between patients and those...

2012-03-20 06:26:22

WASHINGTON, March 20, 2012 /PRNewswire-USNewswire/ -- On Tuesday, March 20, Human Genome Sciences and GlaxoSmithKline released the results of a new survey highlighting a communication gap between people with lupus and the people who care for and about them. The Lupus Foundation of America (LFA) President and Chief Executive Officer, Sandra C. Raymond, issued the following statement regarding the survey results: "Lupus is an unpredictable and incredibly complex disease that can impact every...