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Latest Autoimmunity Stories

2012-08-09 10:28:55

Treatment with generic vaccine kills autoimmune cells, temporarily restoring insulin production A phase I clinical trial has confirmed that use of a generic vaccine to raise levels of an immune system modulator can cause the death of autoimmune cells targeting the insulin-secreting cells of the pancreas and temporarily restore insulin secretion in human patients with type 1 diabetes. Results of the study — led by Denise Faustman, MD, PhD, director of the Massachusetts General...

2012-07-06 10:14:31

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system. The findings, published online ahead of print (June 29, 2012) in the journal Diabetes, suggest for the first time that using a short course of immunotherapy may someday be of value for...

2012-07-06 00:00:14

Chronic inflammatory conditions are extremely common diseases in humans and in the entire animal kingdom. Both in autoimmune diseases and pathogen-caused diseases, the inflamed areas are rapidly colonized by antibody producing B lymphocytes — which organize themselves in highly structured areas called "lymphoid follicles". The scaffold of such follicles is provided by follicular dendritic cells (FDCs). FDCs have important roles in the development of immune responses, since they trap...

Epigenetics Changes Genes In Rheumatoid Arthritis
2012-07-03 12:19:12

It's not just our DNA that makes us susceptible to disease and influences its impact and outcome. Scientists are beginning to realize more and more that important changes in genes that are unrelated to changes in the DNA sequence itself — a field of study known as epigenetics — are equally influential. A research team at the University of California, San Diego — led by Gary S. Firestein, professor in the Division of Rheumatology, Allergy and Immunology at UC San Diego...

2012-06-21 21:02:29

Psoriasis is an autoimmune disorder in which skin cells proliferate out of control. For some hard-to-heal wounds, the problem is just the opposite: Restorative skin cells don't grow well or fast enough. In a paper published in the June 21, 2012 issue of Immunity, researchers at the University of California, San Diego School of Medicine describe a molecule that may lead to new treatments for both problems. An international team of scientists led by principal investigator Richard L. Gallo,...

2012-06-21 20:59:37

Mice carrying a set of friendly microbes that are usually found in humans fail to develop a proper immune system and are left susceptible to illness as a result. The findings in the June 22nd issue of the journal Cell, a Cell Press publication, show that animals have coevolved with and rely on their own very special array of microbial partners. As far as our immune systems are concerned, not just any bug collection will do. "Human microbe-colonized mice have gut immune systems that look...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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