Latest Autophagy Stories
Salmonella is widely prevalent in the animal kingdom.
Whitehead Institute researchers have found that depriving human melanoma cells of the essential amino acid leucine can be lethal to the cells, suggesting a possible strategy for therapeutic intervention.
SAN DIEGO, April 11, 2011 /PRNewswire/ -- Polaris Group (Polaris) announced today that data from preclinical studies of ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, is synergistic with hydroxychloroquine (ChQ) in a human pancreatic cancer cell line and with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in human melanoma cell lines.
Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers.
Dana-Farber Cancer Institute scientists report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis.
Research by the University of Liverpool has found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in a type of roundworm.
Scientists at Trinity College Dublin have made an important discovery concerning how fledgling cancer cells self-destruct, which has the potential of impacting on future cancer therapies.
A protein linked to Parkinson's disease may cause neurodegeneration by inhibiting autophagyâ€”the process in which cells digest some of their contents.
Like some people, cells eat when they are under pressureâ€”but they consume parts of themselves.
A team of researchers, led by Carlos LÃ³pez-OtÃn, at Universidad de Oviedo, Spain, has identified in mice an essential role for the cellular process known as autophagy in inner ear development and balance sensing.
- A transitional zone between two communities containing the characteristic species of each.