Latest Autophagy Stories
Whitehead Institute researchers have found that depriving human melanoma cells of the essential amino acid leucine can be lethal to the cells, suggesting a possible strategy for therapeutic intervention.
SAN DIEGO, April 11, 2011 /PRNewswire/ -- Polaris Group (Polaris) announced today that data from preclinical studies of ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, is synergistic with hydroxychloroquine (ChQ) in a human pancreatic cancer cell line and with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in human melanoma cell lines.
Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers.
Dana-Farber Cancer Institute scientists report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis.
Research by the University of Liverpool has found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in a type of roundworm.
Scientists at Trinity College Dublin have made an important discovery concerning how fledgling cancer cells self-destruct, which has the potential of impacting on future cancer therapies.
A protein linked to Parkinson's disease may cause neurodegeneration by inhibiting autophagyâ€”the process in which cells digest some of their contents.
Like some people, cells eat when they are under pressureâ€”but they consume parts of themselves.
A team of researchers, led by Carlos LÃ³pez-OtÃn, at Universidad de Oviedo, Spain, has identified in mice an essential role for the cellular process known as autophagy in inner ear development and balance sensing.
The liver scarring of Î±1-antitrypsin (AT) deficiency, the most common genetic cause for which children undergo liver transplantation, might be reversed or prevented with a medication that has long been used to treat seizures.
- One of a pair of round metal cymbals attached to the fingers and struck together for rhythm and percussion in belly dancing.