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Last updated on April 16, 2014 at 21:24 EDT

Latest Autosomal dominant polycystic kidney Stories

2013-10-29 08:31:11

3SBio acquires DJ5 patents from Shanghai Institute of Materia Medica SHENYANG, China, Oct. 29, 2013 /PRNewswire/ -- 3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced the acquisition of patents for DJ5, a novel non-TZD PPARgamma agonist with potential to retard progressive renal failure in patients with autosomal dominant polycystic kidney disease ("ADPKD'). 3SBio...

2013-10-03 15:59:37

A new study published today in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts. Known as polycystic kidney disease, this is an inherited disorder which leads to the loss of kidney function, high blood pressure and the need for dialysis. Few treatment options are currently available. The team of scientists from Royal Holloway University, St George's, University of London...

2013-09-06 12:26:52

Study uses induced pluripotent stem cells to identify kidney disease defect New research has uncovered a process that is defective in patients with autosomal dominant polycystic kidney disease, a common cause of kidney failure. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to a new potential strategy for preventing and treating the disease. Polycystic kidney disease (PKD), the fourth leading cause of kidney failure...

2013-07-18 11:17:26

Findings point to new diagnostic category Researchers at Columbia University Medical Center (CUMC) and collaborators have identified a genetic mutation that causes congenital malformations of the kidney and urinary tract, a common form of birth defect and the most common cause of kidney failure in children. It is the first time that a specific genetic mutation has been linked to a non-syndromic form of urinary tract malformation. The findings were published in the July 17 online issue of...

2012-11-05 15:03:03

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say. The medication, tolvaptan, slowed the pace of kidney cyst growth over the three years of the study. The phase three clinical trial results were being presented today at the American Society of Nephrology annual meeting and published online in the New England Journal of Medicine. The multicenter study found tolvaptan...

2012-03-20 10:25:11

KANSAS CITY, Mo., March 20, 2012 /PRNewswire-USNewswire/ -- The PKD Foundation is pleased to announce Michelle Davis has been named Chief Development Officer, effective April 16th. The PKD Foundation is a Kansas City-based nonprofit organization which funds Polycystic Kidney Disease (PKD) research and provides a variety of programs to serve the PKD community. PKD is a lifethreatening genetic disease affecting 12.5 million men, women and children worldwide. Davis brings extensive knowledge...

2011-12-06 23:17:59

Research presented at ASCB annual meeting After a four-week course of the vasodilator hormone relaxin, kidney function and blood flow immediately improved in lab rats genetically altered to model polycystic kidney disease (PKD), a life-threatening genetic disorder, according to research presented on Dec. 6 at the American Society for Cell Biology Annual Meeting in Denver. In addition to widening the blood vessels, relaxin lowered the collagen scores of the PKD rats, indicating that the...

2011-11-03 10:12:00

KANSAS CITY, Mo., Nov. 3, 2011 /PRNewswire-USNewswire/ -- The PKD Foundation is pleased to announce Gary Godsey as its new President and Chief Executive Officer, effective Nov. 28, 2011. The PKD Foundation is a Kansas City-based nonprofit organization which funds Polycystic Kidney Disease (PKD) research and provides a variety of programs to serve the PKD community. PKD is a life-threatening genetic disease affecting 12.5 million men, women and children worldwide. Godsey brings...

2011-10-25 09:46:04

Genetic testing could identify children at risk The most common kidney disease passed down through families, autosomal dominant polycystic kidney disease (ADPKD) affects one in 400 to 1,000 individuals and is characterized by cysts on the kidneys. The condition slowly gets worse and leads to kidney failure. Most ADPKD cases arise in adults, but some patients show severe symptoms of the disease in early childhood. New research indicates that these severely affected patients carry, in...

2011-06-20 12:47:23

A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics. The findings suggest manipulating activity of PKD1, the gene causing the most common form of polycystic kidney disease, may prove beneficial in reducing cysts in both liver and kidney. "We found that these conditions are not the result of an all or nothing phenomenon," said Stefan Somlo, the C.N.H. Long...