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Latest Avastin Stories

2008-07-07 06:00:00

By Gina Kolata and Andrew Pollack It took only an instant for 58-year-old Gailanne Reeh to go from the picture of health to death's door. By chance, her doctor noticed a lump under her arm during a routine exam. It turned out to be advanced breast cancer. Soon she was having tests to reveal the extent of the cancer and hearing the grim results. The surgeon, she recalled, "looked at me and said: 'This is not a conversation I like to have. But I can't do anything for you. You can't be...

2008-07-06 15:00:06

The cancer medication Avastin has been called a wonder drug, but may be less effective than U.S. regulators believed when they approved it. Made by Genentech, Avastin, or bevacizumab, was approved by the U.S. Food and Drug Administration for the use in patients with advanced lung, colon or breast cancer. It works by cutting off tumors' blood supply, The New York Times reported Sunday. In 2004, the medication was approved for combination use with chemotherapy for metastatic colon cancer...

2008-07-06 09:00:06

By GINA KOLATA By Gina Kolata and Andrew Pollack The New York Times It took only an instant for Gailanne Reeh, 58, to go from the picture of health to death's door. By chance, her doctor noticed a lump under her arm during a routine exam. It turned out to be advanced breast cancer. Soon she was having tests to reveal the extent of the cancer and hearing the grim results. The surgeon, she recalled, "looked at me and said: 'This is not a conversation I like to have. But I can't do...

2008-07-01 06:00:49

SAN DIEGO, July 1 /PRNewswire-FirstCall/ -- ADVENTRX Pharmaceuticals, Inc. today announced preliminary response rate results from its discontinued Phase 3 clinical trial of ANX-510, or CoFactor, the Company's folate-based biomodulator of 5-FU (5 fluorouracil), for the treatment of first-line metastatic colorectal cancer. The primary endpoint of the study was progression-free survival, which is expected to mature and be reported by the Company along with safety data later this year. Data...

2007-01-23 15:00:58

Preliminary results show the combination of Xeloda plus Eloxatin, known as XELOX, to be equivalent to standard FOLFOX-4 chemotherapy treatment in terms of overall survival in first-line metastatic colorectal cancer patients. Given its dosing convenience advantage, XELOX has the potential to be a first-line treatment, provided it can be demonstrated as cost-effective. The 2,034 metastatic colorectal cancer patient study was originally designed to compare first-line XELOX (Roche/Chugai's...

2006-08-21 03:00:43

LONDON (Reuters) - Two new targeted therapies for bowel cancer should not be used on Britain's state-run health service, the country's cost-effectiveness watchdog NICE said on Monday. The recommendation angered patient groups, since both Avastin and Erbitux are widely available in the United States and much of Europe. The National Institute for Health and Clinical Excellence (NICE), however, decided the high cost of the medicines meant their use was not "compatible with the best use...

2006-06-05 13:15:42

LOS ANGELES (Reuters) - A mid-stage trial suggests that a combination of cancer drugs Avastin and Tarceva can prolong survival in patients with advanced lung cancer, compared with chemotherapy alone, drug makers Genentech Inc. and OSI Pharmaceuticals said on Monday Avastin, made by Genentech, is the first cancer drug designed to work by cutting off blood supply to tumors. Tarceva, a product of Genentech and OSI, is an oral drug designed to target the human epidermal growth factor...

2006-04-12 01:23:47

ZURICH (Reuters) - Switzerland's Roche has filed for approval in the United States its Avastin cancer drug for treatment of the most widespread form of lung cancer, the drug-maker said on Wednesday. Studies had shown that Avastin was beneficial to patients suffering from non-squamous non-small cell lung cancer -- which accounts for 87 percent of all lung cancer cases in the United States -- in combination with chemotherapy. "Avastin is the first and only treatment in more than a...

2006-03-22 08:33:20

LONDON (Reuters) - Combining the drug Avastin with standard chemotherapy can keep breast cancer under control for longer in patients with advanced disease, scientists said on Wednesday. Avastin, which is made by Roche Holding AG and its majority-owned U.S. biotech arm Genentech Inc, blocks the growth of new blood vessels that are needed for the cancer to grow and spread, or metastasize, beyond the breast. When doctors combined the drug with the chemotherapy treatment Taxol in a study...

2005-10-19 07:19:29

CHICAGO (Reuters) - Genentech Inc. said on Tuesday early results from a mid-stage trial show that combining lung cancer drug Tarceva with Avastin works no better than Avastin alone in patients with advanced kidney cancer, sending shares of Tarceva partner OSI Pharmaceuticals Inc. down 7 percent. As a result, the world's No. 2 biotechnology company said it will not pursue further studies of the Avastin/Tarceva combination in kidney cancer but will continue to analyze the results of...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.