Latest Axon guidance Stories
A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else.
Recent research has shown that Alzheimer's drugs, which are in clinical trials still, have adverse side effects.
Alzheimer's disease drugs now being tested in clinical trials may have potentially adverse side effects.
Biologists at the University of California, San Diego have identified more than 70 genes that play a role in regenerating nerves after injury, providing biomedical researchers with a valuable set of genetic leads for use in developing therapies to repair spinal cord injuries and other common kinds of nerve damage such as stroke.
Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's diseaseâ€”early-onset familial Alzheimer'sâ€”which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets.
Work published today shows that brain cells need to create links early on in their existence, when they are physically close together, to ensure successful connections across the brain throughout life.
USC College's Samantha Butler and collaborators show that the rate and direction of axon growth in the spinal cord can be controlled, a discovery that one day may help improve treatment for spinal injuries or neurodegenerative diseases.
Tuberous sclerosis, commonly associated with autism, is linked to defects in axon guidance.
Scientists at the University of California, San Diego School of Medicine have demonstrated the ability to correctly re-wire connections to the spinal cord after spinal cord injury.
The research group of Dr. FrÃ©dÃ©ric Charron, a researcher at the Institut de recherches cliniques de MontrÃ©al (IRCM), has made a discovery which could help treat spinal cord injuries and neurodegenerative diseases.