Quantcast

Latest Axon Stories

2013-01-08 10:05:13

Insect research yields insights for muscle control and nerve disorders in mammals, including humans Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect to their correct muscle targets. The proteins´ mammalian counterparts are known to have signaling roles in immunity, nervous system and heart development, and tumor progression, suggesting broad...

2012-11-01 23:10:49

A gene that is associated with regeneration of injured nerve cells has been identified by scientists at Penn State University and Duke University. The team, led by Melissa Rolls, an assistant professor of biochemistry and molecular biology at Penn State, has found that a mutation in a single gene can entirely shut down the process by which axons -- the parts of the nerve cell that are responsible for sending signals to other cells -- regrow themselves after being cut or damaged. "We are...

2012-10-30 12:35:05

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases. In Lou Gehrig's Disease (ALS) and other neurodegenerative diseases, nerve cells usually die in stages, with axons deteriorating first and the cells themselves perishing later. Axon degeneration may represent a...

2012-08-01 11:33:14

Wayne State University School of Medicine researchers, working with colleagues in Canada, have found that one or more substances produced by a type of immune cell in people with multiple sclerosis (MS) may play a role in the disease's progression. The finding could lead to new targeted therapies for MS treatment. B cells, said Robert Lisak, M.D., professor of neurology at Wayne State and lead author of the study, are a subset of lymphocytes (a type of circulating white blood cell) that...

2012-07-26 01:06:23

Several years ago, Prof. Michael Fainzilber and his group in the Biological Chemistry Department made a surprising discovery: Proteins thought to exist only near the cell nucleus could also be found in the far-off regions of the body's longest cells — peripheral nerve cells that extend processes called axons, reaching up to a meter in length in adult humans. These proteins, known as importins, have a well-studied role in the vicinity of the nucleus: They shuttle various molecules...

2012-07-20 12:31:18

Korean scientists have used tiny stars, squares and triangles as a toolkit to create live neural circuits in a dish. They hope the shapes can be used to create a reproducible neural circuit model that could be used for learning and memory studies as well as drug screening applications; the shapes could also be integrated into the latest neural tissue scaffolds to aid the regeneration of neurons at injured sites in the body, such as the spinal cord. Published today, 20 July, in IOP...

2012-06-07 08:33:20

Research shows mice brains are 'very wired up' at birth, and suggests experience selects which connections to keep Ask the average person the street how the brain develops, and they'll likely tell you that the brain's wiring is built as newborns first begin to experience the world. With more experience, those connections are strengthened, and new branches are built as they learn and grow. A new study conducted in a Harvard lab, however, suggests that just the opposite is true. As...

2012-05-31 01:40:25

A molecule responsible for the proper formation and function of neurons finds its way to the right place not because it is actively recruited, but because it can't go anywhere else. Researchers at Baylor College of Medicine have identified a distal axonal cytoskeleton that functions as a boundary to ensure a key scaffolding protein, called ankyrinG, stays at the start of the axon near the cell body where it performs its functions of clustering sodium and potassium ion channels and...

2012-05-24 21:13:07

A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else. Researchers at Baylor College of Medicine have identified a distal axonal cytoskeleton as the boundary that makes sure AnkyrinG clusters where it needs to so it can perform properly. "It has been known that AnkyrinG is needed for the axon initial segment to form. Without the axon...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
Related