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Latest Axon Stories

2011-03-23 20:41:03

A new study is providing fascinating insight into how projections conveying sensory information in the brain are guided to their appropriate targets in different species. The research, published by Cell Press in the March 24 issue of the journal Neuron, reveals a surprising new evolutionary scenario that may help to explain how subtle changes in the migration of "guidepost" neurons underlie major differences in brain connectivity between mammals and nonmammalian vertebrates. The neocortex...

2011-02-18 12:31:04

Findings challenge conventional wisdom of how neurons operate Neurons are complicated, but the basic functional concept is that synapses transmit electrical signals to the dendrites and cell body (input), and axons carry signals away (output). In one of many surprise findings, Northwestern University scientists have discovered that axons can operate in reverse: they can send signals to the cell body, too. It also turns out axons can talk to each other. Before sending signals in reverse, axons...

2011-02-14 16:26:20

Neurobiologists at UC San Diego have discovered new ways by which nerves are guided to grow in highly directed ways to wire the brain during embryonic development. Their finding, detailed in a paper in the February 15 issue of the journal Developmental Cell, provides a critical piece of understanding to the longstanding puzzle of how the human brain wires itself into the complex networks that underlie our behavior. The discovery concerns the movements of a highly sensitive and motile...

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2011-02-14 10:44:59

The human brain consists of approximately one hundred billion nerve cells. Each of these cells needs to connect to specific other cells during the brain's development in order to form a fully functional organism. Yet how does a nerve cell know where it should grow and which cells to contact? Scientists of the Max Planck Institute of Neurobiology in Martinsried have now shown that growing nerve cells realize when they've reached their target area in the fly brain thanks to the interaction of...

2011-01-26 20:35:14

New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses. New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses. The findings appear online Jan. 27, 2011 in the journal Neuron. Our hard-wired nerve fibers or...

2011-01-26 17:36:20

The research may lead to a better understanding of diseases such as autism and schizophrenia Connected highways of nerve cells carry information to and from different areas of the brain and the rest of the nervous system. Scientists are trying to draw a complete atlas of these connections"”sometimes referred to as the "connectome""”to gain a better understanding of how the brain functions in health and disease. New research conducted at The Scripps Research Institute shows that...

2011-01-19 14:09:55

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease"”early-onset familial Alzheimer's"”which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets. Without it, budding motor neurons misread their guidance signals and get...

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2010-12-10 08:12:58

By Katrina Voss, Penn State A team of scientists led by Melissa Rolls, an assistant professor of biochemistry and molecular biology at Penn State University, has peered inside neurons to discover an unexpected process that is required for regeneration after severe neuron injury. The process was discovered during Rolls's studies aimed at deciphering the inner workings of dendrites -- the part of the neuron that receives information from other cells and from the outside world. The research will...

2010-11-22 19:45:57

A team of Brandeis scientists makes breakthrough with mutant gene that causes familial form of Lou Gehrig's disease Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that eventually destroys most motor neurons, causing muscle weakness and atrophy throughout the body. There is no cure and the current treatment has only a moderate effect on the march of the disease, which typically kills within three to five years. This week in PNAS, a team of Brandeis scientists reports...

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2010-11-18 10:49:42

By Laurie Moore, University of Southern California USC College's Samantha Butler and collaborators show that the rate and direction of axon growth in the spinal cord can be controlled, a discovery that one day may help improve treatment for spinal injuries or neurodegenerative diseases. Both the rate and direction of axon growth in the spinal cord can be controlled, according to new research by USC College's Samantha Butler and her collaborators. The study, "The Bone Morphogenetic Protein...


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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