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Latest Axon Stories

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2009-12-29 10:31:00

By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits. Details of the observation in lab mice, published Dec. 24 in Nature, reveal that semaphorin, a protein found in the developing nervous system that guides filament-like processes, called axons, from nerve cells to their appropriate...

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2009-12-10 08:35:00

Mouse study suggests that response to injury-induced growth factors can be revived Brain and spinal-cord injuries typically leave people with permanent impairment because the injured nerve fibers (axons) cannot regrow. A study from Children's Hospital Boston, published in the December 10 issue of the journal Neuron, shows that axons can regenerate vigorously in a mouse model when a gene that suppresses natural growth factors is deleted. Adding to a previous study published in Science last...

2009-12-06 13:51:03

Structurally, functionally different cell component replaces injured part Studies with fruit flies have shown that the specialized nerve cells called neurons can rebuild themselves after injury. These results, potentially relevant to research efforts to improve the treatment of patients with traumatic nerve damage or neurodegenerative disease, were presented at the American Society for Cell Biology (ASCB) 49th Annual Meeting, Dec. 5-9, 2009 in San Diego. An injured neuron's remarkable ability...

2009-12-02 19:18:29

If the entrances and exits of freeways shut down, traffic all over the United States would come to a halt. In a similar situation, injuries to the brain can make it impossible for neurons to determine information input from output and impedes the ability of the nervous system to operate. In a recent report in The Journal of Neuroscience, researchers at Baylor College of Medicine and the University of Connecticut Health Center show that this is exactly what happens after nervous system...

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2009-11-09 07:26:46

Researchers at Purdue University have discovered a new approach for repairing damaged nerve fibers in spinal cord injuries using nano-spheres that could be injected into the blood shortly after an accident. The synthetic "copolymer micelles" are drug-delivery spheres about 60 nanometers in diameter, or roughly 100 times smaller than the diameter of a red blood cell. Researchers have been studying how to deliver drugs for cancer treatment and other therapies using these spheres. Medications...

2009-10-28 22:05:28

Scientists at the University of California, San Diego School of Medicine report that regeneration of central nervous system axons can be achieved in rats even when treatment delayed is more than a year after the original spinal cord injury. "The good news is that when axons have been cut due to spinal cord injury, they can be coaxed to regenerate if a combination of treatments is applied," said lead author Mark Tuszynski, MD, PhD, professor of neurosciences and director of the Center for...

2009-10-28 22:02:03

New research finds that adult neurons can still regenerate as long as 15 months after a spinal cord injury. The study, published by Cell Press in the October 29th issue of the journal Neuron, highlights the success of a strategy that targets multiple environmental and intrinsic obstacles known to limit nervous system plasticity and regeneration. "Despite advances in promoting axonal regeneration after acute spinal cord injury, elicitation of regeneration of key neuronal processes, called...

2009-10-26 14:46:40

Enzyme could lead to a possible treatment for brain and spinal cord injury Researchers at Children's Hospital Boston report that an enzyme known as Mst3b, previously identified in their lab, is essential for regenerating damaged axons (nerve fibers) in a live animal model, in both the peripheral and central nervous systems. Their findings, published online by Nature Neuroscience on October 25, suggest Mst3b "“ or agents that stimulate it "“ as a possible means of treating stroke,...

2009-10-23 14:33:35

Neurons are structurally complex, with specific parts of the cell responsible for information input and other parts responsible for information output. When neurons lose the ability to distinguish between inputs and outputs, the nervous system stops working. In a report published today in The Journal of Neuroscience, researchers at Baylor College of Medicine and the University of Connecticut Health Center show that this is exactly what happens after nervous system injury. "This is a new way...

2009-10-22 14:00:00

Johns Hopkins scientists show how tiny cells deliver big sound Deep in the ear, 95 percent of the cells that shuttle sound to the brain are big, boisterous neurons that, to date, have explained most of what scientists know about how hearing works. Whether a rare, whisper-small second set of cells also carry signals from the inner ear to the brain and have a real role in processing sound has been a matter of debate. Now, reporting on rat experiments in the October 22 issue of Nature, a Johns...


Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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