Latest Aziz Sancar Stories

2011-07-26 09:57:15

Researchers who have been working for nearly a decade to piece together the process by which an enzyme repairs sun-damaged DNA have finally witnessed the entire process in full detail in the laboratory. What they saw contradicts fundamental notions of how key biological molecules break up during the repair of sunburn "“ and that knowledge could someday lead to drugs or even lotions that could heal sunburn in humans. In the Proceedings of the National Academy of Sciences (PNAS), the Ohio...

2010-12-29 13:54:04

In a new paper published this week in the Proceedings of the National Academy of Sciences, Aziz Sancar, MD, PhD, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, and his colleagues have taken an important step in understanding the underlying molecular signals that influence a broad array of biological processes ranging from the sleep-wake cycle to cancer growth and development. Scientists who work in this field, known as chronobiology, have...

2009-02-05 23:01:30

Disrupting the body's time-keeping system, the circadian clock, may help slow cancer growth, U.S. researchers say. In a mouse model used to investigate cancer, genetically altering one of four essential clock genes suppressed cancer growth -- perhaps due to intracellular signals that make cancer cells more likely to commit cell suicide -- a process known as apoptosis. Adjusting the clock in this way could certainly be a new target for cancer treatment, senior study author Dr. Aziz Sancar of...

2009-02-03 15:07:27

Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock "“ the internal time-keeping mechanism that keeps the body running on a 24-hour cycle "“ can slow the progression of cancer.The study disputes some of the most recent research in the field indicating that alteration of this daily cycle predisposes humans and mice to cancer. The UNC researchers found that genetically altering one of four essential "clock" genes actually...

2009-01-13 13:05:13

For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival. But the lack of a clear scientific explanation for this finding has kept clinicians from considering timing as a factor in treatment. Now, a new study from the University of North Carolina at Chapel Hill has suggested that treatment is most effective at certain times of day because that is when a particular enzyme system "“ one that can reverse the actions...

Word of the Day
  • Good cheer; viands.
  • To revel; to feast.
The word 'bellycheer' may come from 'belle cheer', "good cheer".