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Last updated on April 16, 2014 at 17:34 EDT

Latest B cell Stories

2014-04-03 08:29:54

Novel methodology leverages somatic hypermutation to rapidly generate humanized therapeutic antibodies with >97% human content SAN DIEGO, April 3, 2014 /PRNewswire/ -- AnaptysBio, Inc., a leader in the discovery and development of therapeutic antibodies, announced today that the U.S. Patent and Trademark Office (USPTO) has issued US Patent #8,685,897 broadly covering a novel approach to antibody humanization using somatic hypermutation. Leveraging key advantages of AnaptysBio's...

2014-03-11 16:25:50

AUSTIN, Texas, March 11, 2014 /PRNewswire/ -- XBiotech announced today that the United States Patent and Trademark Office (USPTO) granted another key patent to support the Company's growing portfolio around its lead product candidate. The new patent grants XBiotech exclusive rights to target a unique molecule associated with chronic sterile inflammation. The patent relates to antibodies and methods of using these antibodies to treat, prevent, and detect disease progression associated...

2014-02-24 08:05:42

IMIM (Hospital del Mar Medical Research Institute) This discovery clears the path to developing more efficient vaccines against meningitis and pneumonia, responsible for the death of millions of children every year Researchers have discovered the presence of a novel subtype of innate lymphoid cells in human spleen essential for the production of antibodies. This discovery, published in the prestigious journal Nature Immunology, clears the path to the identification of novel strategies...

2014-02-06 16:26:57

LA JOLLA, Calif., Feb. 6, 2014 /PRNewswire-USNewswire/ -- A team led by scientists at The Scripps Research Institute (TSRI) has discovered an unusual bacterial protein that attaches to virtually any antibody and prevents it from binding to its target. Protein M, as it is called, probably helps some bacteria evade the immune response and establish long-term infections. If follow-up studies confirm Protein M's ability to defeat the antibody response, it is likely to become a target of...

2014-01-30 16:26:47

HAYWARD, Calif., Jan. 30, 2014 /PRNewswire/ -- Anthera Pharmaceuticals, Inc. (NASDAQ:ANTH), a biopharmaceutical company focused on developing and commercializing products to treat autoimmune diseases, announced today that Paul F. Truex, President and Chief Executive Officer, will present a corporate update on the progress of the Company's development programs including additional plans for blisibimod beyond autoimmune disorders at three conferences in February and early March. Investor...

2014-01-08 12:29:43

SEATTLE, Jan. 8, 2014 /PRNewswire/ -- Adaptive Biotechnologies (www.adaptivebiotech.com) announced today that Chad Robins, Founder and Chief Executive Officer, is scheduled to present a company overview at the 32(nd) Annual J.P. Morgan Healthcare Conference in San Francisco on Wednesday, January 15(th), 2014 at 2:00pm PST. (Logo: http://photos.prnewswire.com/prnh/20120103/SF28632LOGO) About AdaptiveAdaptive Biotechnologies Corporation ("Adaptive" or the "Company") is a pioneer in...

2013-11-04 09:13:55

Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 on coated B cells, which induces B cell deletion through a mechanism that is not clearly understood. In this issue of the Journal of Clinical Investigation, Philippe Bousse and colleagues at the Pasteur Institute in Paris described the fate of B cells in live mice after...

2013-10-25 16:24:09

Company develops Synthetic Immune System (SIS(TM)) to control for possible bias inherent in high-throughput immune sequencing; aims to develop kit for widespread distribution SEATTLE, Oct. 25, 2013 /PRNewswire/ -- Adaptive Biotechnologies Corporation, a leading provider of next-generation oncology diagnostics, announced today the publication of a method to significantly improve the accuracy of next-generation immune system profiling by creating a fully validated Synthetic Immune...

2013-08-21 12:28:02

Mirrors the influence of gut bacteria over T-cells, suggests new paradigm for B-cell development BOSTON, Aug. 21, 2013 /PRNewswire-USNewswire/ -- Gut bacteria exert a dramatic, systemic effect on the development of the immune system's B-lymphocytes, according to a new mouse study by researchers at Boston Children's Hospital. While influences of gut bacteria on T-lymphocytes have been noted before, this is the first time that researchers have documented early B-cell development in...

Ancient Immune Cells In Lampreys Similar To Ours, But More Complex
2013-08-13 08:06:38

April Flowers for redOrbit.com - Your Universe Online When biologists study lampreys, they are able to envision the evolutionary past because these jawless specimens represent an early offshoot to the evolutionary tree, before sharks and fish. They have an inconspicuous appearance, but a sophisticated immune system with three types of white blood cells that resemble our B and T cells. A new study from Emory University School of Medicine and the Max Planck Institute of Immunology and...