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Latest B cell Stories

2010-09-15 19:08:42

A new focus on the immune system's ability to both unleash and restrain its attack on disease has led Dana-Farber Cancer Institute scientists to identify cells in mice that prevent the immune system from attacking the animals' own cells, protecting them from autoimmune diseases such as multiple sclerosis, type 1 diabetes, and lupus. The discovery, reported online on Sept. 16 by the journal Nature, may give scientists an effective way of operating the immune system's internal "control panel,"...

2010-09-08 14:41:16

Scientists from the University of California, San Diego School of Medicine have identified dendritic antigen-presenting cells in zebrafish, opening the possibility that the tiny fish could become a new model for studying the complexities of the human immune system. The study, reported in the online edition of the Proceedings of the National Academy of Sciences, was headed by David Traver, an associate professor in UCSD's Department of Cellular and Molecular Medicine, with colleagues in UCSD's...

2010-06-15 15:12:16

Scientists have long known that certain types of bacteria boost the immune system. Now, Loyola University Health System researchers have discovered how bacteria perform this essential task. Senior author Katherine L. Knight, PhD. and colleagues report their discovery in a featured article in the June 15, 2010, issue of the Journal of Immunology, now available online. Knight is professor and chair of the Department of Microbiology and Immunology at Loyola University Chicago Stritch School of...

2010-05-24 14:53:06

A cell small in number but powerful in its ability to switch the immune system on or off is a unique hybrid of two well-known immune cell types, Medical College of Georgia researchers report. "This is actually the first cell we know of that has this type of appearance in nature," Dr. Andrew Mellor, molecular geneticist and immunologist who co-directs MCG's Immunotherapy Discovery Institute, said of the cell that looks like a dendritic cell and a B cell but isn't really either. The discovery...

2010-05-14 11:39:49

Members of a population of identical cells often "choose" different fates, even though they exist in identical conditions. The difference may rest with the "hidden variables" within the cells, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Cell. That finding, tested in bacterial cells of Escherichia coli infected with viruses called bacteriophage lambda, challenges the commonly held belief that the differences in fate rest with...

2010-05-11 11:54:25

Asthma and other allergic diseases are caused by inappropriate immune responses. Soluble IgE molecules, produced by immune cells known as B cells, are key immune mediators of these diseases. Therapeutic targeting of IgE in the blood can neutralize its effects and is an effective treatment for moderate-to-severe allergic asthma. However, this approach does not halt IgE production and patients need to be treated repeatedly. But now, a team of researchers, at Genentech Inc., South San Francisco,...

2010-05-04 14:01:51

Researchers at Karolinska Institutet have discovered a new control mechanism in our immune system. The discovery is of potential significance to the treatment of serious diseases such as MS (multiple sclerosis), rheumatoid arthritis, and SLE (Systemic lupus erythematosus). "Now that we've started to understand the regulatory mechanisms involved in these autoimmune diseases, we are hopeful that new treatments can be found," says Mikael Karlsson, associate professor at the Department of...

2010-03-22 08:08:00

New research may guide creation of targeted, more effective vaccines BOSTON, March 22 /PRNewswire-USNewswire/ -- A new understanding of a certain cell in the immune system may help guide scientists in creating better flu vaccines, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI). Reporting online March 21 in Nature Immunology, they show, for the first time, that white blood cells known as...

2010-01-20 15:09:45

Study shows: Nutrition has a direct influence on the immune system Bonn researchers have discovered an elementary mechanism which regulates vital immune functions in healthy people. In situations of hunger which mean stress for the body's cells, the body releases more antimicrobial peptides in order to protect itself. The scientists will publish their results in the journal Nature. T cells, B cells, antibodies are known as the 'SWAT team' of our immune system that intervenes when viruses and...

2009-12-22 13:35:38

Antibodies directed against the protein CD20, which is expressed by immune cells known as B cells, are used to treat B cell non-Hodgkin lymphoma and rheumatoid arthritis. Despite this, the function of CD20 has not been determined. Now, a team of researchers led by Ren© van Lier, at the Academic Medical Center, The Netherlands, has determined that CD20 has a nonredundant role in generating optimal B cell immune responses by analyzing a patient lacking the protein. The patient was referred...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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