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Latest B cell Stories

2009-04-30 09:37:27

Scientists believe they may have found a preventative therapy for Type 1 diabetes, by making the body's killer immune cells tolerate the insulin-producing cells they would normally attack and destroy, prior to disease onset.Type 1 diabetes is an autoimmune condition, where the body attacks its own insulin producing cells. It is very serious, with a sudden and dramatic onset, usually in youth. People with Type 1 diabetes must maintain an insulin-monitoring and insulin-injecting regimen for the...

2009-04-02 10:59:31

For years, researchers and physicians have known that infants' immune systems do not respond well to certain vaccines, thus the need for additional boosters as children develop. Now, in a new study from the University of Missouri, one researcher has found an explanation for that poor response. In the study, the MU scientist found evidence that the immune systems of newborns might require some time after birth to mature to a point where the benefits of vaccines can be fully realized.Habib...

2009-01-24 14:30:47

Scientists at UCSF have discovered an abnormality in a patient's immune system that may lead to safer therapies for autoimmune diseases such as rheumatoid arthritis and colitis, as well as potential new ways to treat transplant rejection. The research identified antibodies from a woman's immune system that prevent infection-fighting T cells from moving through her blood stream and entering her body's organs to attack invaders such as bacteria or viruses. Findings appear in the current online...

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2009-01-05 09:23:00

MIT engineers have developed a new, highly efficient way to pair up cells so they can be fused together into a hybrid cell. The new technique should make it much easier for scientists to study what happens when two cells are combined. For example, fusing an adult cell and an embryonic stem cell allows researchers to study the genetic reprogramming that occurs in such hybrids. The researchers, led by a collaboration between Joel Voldman, associate professor of electrical engineering and...

2009-01-02 12:31:07

The self-attacking cells to blame for autoimmune diseases could be on the loose in all of us. Researchers found healthy adults without autoimmune diseases like lupus and rheumatoid arthritis may have anergic B cells "“ the self-attacking B cells behind autoimmune diseases -- that account for as many as 2.5 percent of the B cells in our blood stream. The difference, they found, is the anergic B cells in healthy people are maintained in an "Ëœoff' state. Usually, study authors...

2008-12-23 14:44:24

Implications for new tests and more personalized treatments for autoimmune diseases More drafts usually mean a better product and so it also seems to go with the human immune system. As B cells develop, genes rearrange to allow their antibodies to recognize different foreign invaders or pathogens. But sometimes antibodies are created that recognize and attack the body's own cells. These self-reactive antibodies, like early drafts of a manuscript, must be edited into safer versions. This...

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2008-12-23 10:41:11

Artificial bone marrow that can continuously make red and white blood cells has been created in a University of Michigan lab. This development could lead to simpler pharmaceutical drug testing, closer study of immune system defects and a continuous supply of blood for transfusions. The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body, said Nicholas Kotov, a professor in the U-M departments of Chemical Engineering; Materials Science and Engineering;...

2008-12-22 16:00:59

Potential autoimmunity-inducing cells have been found in healthy humans as well patients with autoimmune diseases such as lupus, U.S. researchers report. Whether these cells are precursors to the self-attacking cells prevalent in lupus and rheumatoid arthritis remains unknown, researchers lead by J. Andrew Duty at the Oklahoma Medical Research Foundation reported in a news release. As antibody-producing B cells develop in the bone marrow, the body tests them to determine whether they confuse...

2008-12-22 10:00:00

It's not just patients with autoimmune diseases like lupus and rheumatoid arthritis (RA) that have self-attacking immune cells"”healthy people have them too, according to a new report in the Journal of Experimental Medicine. In healthy adults, however, these cells are maintained in an 'off' state, perhaps explaining their innocuous nature. Whether these cells are the true predecessors of the self-attacking cells prevalent in lupus and RA and, if so, what prevents them from causing...

2008-12-11 10:05:50

More than five million people die every year from infectious diseases, despite the availability of numerous antibiotics and vaccines. The discovery of penicillin to treat bacterial infections, along with the development of vaccines for previously incurable virus diseases such as polio and smallpox, achieved great reductions in mortality during the mid-20th century. Recently, spectacular advances in medical imaging combined with mathematical tools for modeling the human immune system have...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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