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Latest Bacillus Calmette-Guérin Stories

2012-03-20 11:25:48

In the past decade, scientists have made significant progress building the critical knowledge and infrastructure needed to identify and develop novel tuberculosis (TB) vaccine candidates and move the most promising ones into human clinical trials. The results of those trials, coupled with advances from other TB studies, have paved the way for the next 10 years of research on TB vaccines, a critical component of TB control efforts, note scientists at the National Institute of Allergy and...

2011-12-02 01:46:06

The World Health Organization estimates that one-third of the world's population is currently infected with the microbe that causes tuberculosis, Mycobacterium tuberculosis. The only vaccine, BCG, is largely ineffective; ways to enhance its effectiveness are desperately needed. A team of researchers – led by Peter Andersen, at Statens Serum Institut, Denmark, and JoAnne L. Flynn, at the University of Pittsburgh School of Medicine, Pittsburgh, – has now developed a vaccine that...

2011-11-07 16:17:35

The incidence of tuberculosis (TB) in the U.S. is reported as being on the decrease, however untreated infected people act as a reservoir for disease. Any pool of the world's population harboring this disease gives cause for concern, especially since the BCG vaccine is only 70-80% effective at best. New research published in BioMed Central's open access journal BMC Public Health, shows that in 2009 the number of cases of TB reported across America was much lower than that recorded in previous...

2011-09-08 10:14:31

(Ivanhoe Newswire) — A potential vaccine against tuberculosis (TB) has been found to completely eliminate TB bacteria from infected tissues in some mice. The vaccine was made from a strain of bacteria that are unable to avoid its host´s first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that remembers the bacteria and protects against future infection. Tuberculosis, an infectious disease caused by...

2011-09-06 12:45:41

  An experimental vaccine composed of a genetically modified bacterium closely related to the bacterium that causes tuberculosis (TB) has been found to protect mice against TB infection, according to a study appearing online September 4 in the journal Nature Medicine. The research was funded in part by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health. TB, a respiratory disease that according to World Health Organization estimates...

2011-09-05 11:16:45

A potential vaccine against tuberculosis has been found to completely eliminate tuberculosis bacteria from infected tissues in some mice. The vaccine was created with a strain of bacteria that, due to the absence of a few genes, are unable to avoid its host's first-line immune response. Once this first-line defense has been activated, it triggers the more specific immune response that can protect against future infections. The research, by scientists at the Howard Hughes Medical Institute,...

2011-06-27 14:15:49

Generic drug reproduces mechanism that reversed diabetes in mice, Phase II trial now underway Promising results of the Phase I clinical trial of the generic drug BCG (bacillus Calmette-Guerin) to treat advanced type I diabetes were announced today at the American Diabetes Association scientific sessions in San Diego. A research team led by Denise Faustman, MD, PhD, director of the Massachusetts General Hospital (MGH) Immunobiology Laboratory is presenting two abstracts (No. 2240-PO and No....


Latest Bacillus Calmette-Guérin Reference Libraries

45_255d6ba67dfe6f32b9c7c31f338bf912
2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

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Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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