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Latest Bacillus Calmette-Guérin Stories

2011-05-11 19:14:07

McGill research team found 2 distinct disease-causing mutations and saved a baby girl About two years ago, Dr. Philippe Gros, a McGill University professor in the Department of Biochemistry and a Principal Investigator in thd McGill Life Sciences Complex, described a mouse mutant that was immunodeficient and hypersensitive to the Bacille Calmette-Gu©rin (BCG) vaccine and to tuberculosis (TB). In this model, Gros's team had found that the immunodeficiency was caused by a mutation in a...

2011-03-22 23:28:05

In this week's PLoS Medicine, and to coincide with World TB Day, Madhukar Pai from McGill University in Montreal, Canada and colleagues introduce the BCG World Atlas, an open access, user friendly website for TB clinicians to discern global BCG vaccination policies and practices and improve the care of their patients. The Bacille Calmette-Gu©rin (BCG) vaccine continues to be controversial, with known variations in BCG substrains and vaccine efficacy. Vaccine policies and practices vary...

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2011-03-21 07:25:00

Scientists have discovered a protein secreted by tuberculosis (TB) bacteria that could be a promising new vaccine candidate, they report in the March 18 issue of Proceedings of the National Academy of Sciences. The protein could also be used to improve diagnosis of TB. TB is caused by the bacterium Mycobacterium tuberculosis (MTB), which infects the lungs and spreads through the air as a result of coughing. There are 9 million new cases of TB each year, killing 4,700 people a day worldwide....

2011-02-18 16:05:50

Nele Festjens and Nico Callewaert of VIB and Ghent University have improved the efficacy of the vaccine for tuberculosis. The new vaccine affords - as already proven in mice - better protection against the disease. The development of a new tuberculosis vaccine is a priority in the fight against the disease which claims the lives of 1.7 million people each year. The current vaccine provides only partial protection. Nico Callewaert: "Our vaccine is more effective because it is more quickly...

2011-02-17 17:00:00

CHADDS FORD, Pa. and BELLEVILLE, Ontario, Feb. 17, 2011 /PRNewswire/ -- Endo Pharmaceuticals (Nasdaq: ENDP) and Bioniche Life Sciences Inc. (TSX and ASX: BNC) today announced plans for peer-reviewed presentation of interim efficacy and safety results from the first Phase III trial of the intravesical formulation of Mycobacterial cell wall-DNA complex (MCC), known as Urocidin(TM) or EN3348. The results to be presented have been generated from an ongoing Phase III registration trial with...

2011-02-15 08:29:00

THE HAGUE, The Netherlands, February 15, 2011 /PRNewswire/ -- - The Ministry of Health, Welfare and Sport (Ministerie van Volkgezondheid, Welzijn en Sport) has Announced That it Commences With the Sale of the Production Activities of the 'Nederlands Vaccin Instituut' (NVI). The Sales Process Starts on February 15, 2011. In January 2010 the Minister of Health, Welfare and Sport informed the House of Representatives that the NVI was going to change course. NVI's public tasks,...

2011-01-25 13:09:58

WHAT: A team of U.S. and European researchers have found that a new vaccine strategy tested in mice provides stronger, more long-lasting protection from tuberculosis (TB) infection than the vaccine currently used in humans, known as BCG. Their findings were published online on January 23rd in the journal Nature Medicine. The study was co-funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the Bill & Melinda Gates...

2010-12-01 21:09:00

New research published in the Journal of Leukocyte Biology suggests that the effectiveness of the bacille Calmette-Guerin vaccine is compromised by environmental bacteria A new discovery may explain why a tuberculosis vaccine is not as effective for some people as anticipated, and potentially explains why other vaccines do not work as well for some as they do for others. In a research report presented in the December 2010 issue of the Journal of Leukocyte Biology (http://www.jleukbio.org),...

2010-10-15 23:00:00

SEATTLE, Oct. 16 /PRNewswire-USNewswire/ -- The Infectious Disease Research Institute (IDRI) announces it has developed a new tuberculosis (TB) vaccine that protects against TB including drug-resistant strains of the disease in animal studies. The results of these studies are published in Science Translational Medicine today. Drug-resistant tuberculosis is a major global public health concern. According to the World Health Organization, approximately 9 million people are infected with TB,...

2010-09-23 12:33:02

At an international gathering of TB vaccine researchers in Tallinn today, the Aeras Global TB Vaccine Foundation announced it will initiate a clinical trial of an investigational live recombinant tuberculosis vaccine to be led by researchers at Saint Louis University in St. Louis, Missouri, USA.  The announcement was made at the Second Global Forum on TB Vaccine Development. Building on more than a decade of global scientific research, Aeras scientists have engineered a new...


Latest Bacillus Calmette-Guérin Reference Libraries

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2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

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