Latest Bacteria Stories
New research led by the Karolinska Institutet, Sweden and the University of Glasgow, Scotland, has identified a link between a human gene and the composition of human gastrointestinal bacteria. In a study published as a letter to the journal Gut, the team outline new evidence suggesting that the human genome may play a role in determining the makeup of the billions of microbes in the human gastrointestinal tract collectively known as the gut microbiota. Mauro D'Amato, Associate Professor...
SEOUL, South Korea, Jan. 7, 2013 /PRNewswire/ -- CrystalGenomics, Inc., a clinical stage biopharmaceutical company headquartered in Korea, has just announced that it has received the draft of the Clinical Study Report (CSR) from the recently completed Phase 2a study of CG400549, a first-in-class antibiotic candidate for Methicillin-resistant Staphylococcus aureus (MRSA). This study was the first human efficacy study for CG400549 and was an open-label, exploratory study to...
SAN FRANCISCO, Jan. 7, 2013 /PRNewswire/ -- Second Genome announced today an initiative with the American Gut project to explore the connection between the human microbiome and type 2 diabetes. The cooperation will bring together American Gut's broad citizen science network for microbiome sample collection with Second Genome's efforts in identifying microbiome modulators and novel therapeutics. Second Genome has made an undisclosed donation to American Gut to subsidize specimen...
NEW YORK, Jan. 3, 2013 /PRNewswire/ -- Dipexium Pharmaceuticals, LLC today announced that it has reached an agreement with the U.S. Food and Drug Administration ("FDA") on a Special Protocol Assessment ("SPA") for an upcoming Phase 3 registration trial in mild infections of diabetic foot ulcers with Locilex(TM) (pexiganan acetate cream 1%), an antibiotic peptide formulated as a topical cream. The SPA agreement states that the proposed trial protocol design, clinical endpoints and...
Brett Smith for redOrbit.com - Your Universe Online In a sun-scorched region of Western Australia known as Pilbara, a team of American and Australian paleobiologists believe they have located the oldest known evidence of life on Earth. The ancient bacterial fossils have been dated as 3.49 billion years old, only about a billion years after scientists estimate the Earth was formed. “It’s not just finding this stuff that’s interesting,” said Alan Decho, a geobiologist at the...
HORSHAM, Pa., Jan. 2, 2013 /PRNewswire/ -- A new study conducted by infection control experts at Johns Hopkins Hospital demonstrates that patients admitted to hospital rooms decontaminated using Bioquell hydrogen peroxide vapor technology, rather than standard cleaning protocols, were significantly less likely to acquire multidrug-resistant organisms (MDROs), or so-called hospital superbugs. The study is published in this month's issue of Clinical Infectious Diseases. The Bioquell...
Johns Hopkins to begin decontaminating isolation rooms with robotic, vapor-dispersing devices Infection control experts at The Johns Hopkins Hospital have found that a combination of robot-like devices that disperse a bleaching agent into the air and then detoxify the disinfecting chemical are highly effective at killing and preventing the spread of multiple-drug-resistant bacteria, or so-called hospital superbugs. A study report on the use of hydrogen peroxide vaporizers -- first...
One approach to understanding components in living organisms is to attempt to create them artificially, using principles of chemistry, engineering and genetics. A suite of powerful techniques—collectively referred to as synthetic biology—have been used to produce self-replicating molecules, artificial pathways in living systems and organisms bearing synthetic genomes. In a new twist, John Chaput, a researcher at Arizona State University’s Biodesign Institute and colleagues at the...
SUNNYVALE, Calif., Dec. 27, 2012 /PRNewswire/ -- Cepheid (NASDAQ: CPHD) today announced that it has received clearance from the U.S. Food & Drug Administration (FDA) to market Xpert(®) CT/NG. Running on Cepheid's GeneXpert(®) Systems, Xpert CT/NG is a qualitative in vitro molecular diagnostic test for the detection and differentiation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG). For the first time, same-day patient consultation and treatment is possible for...
4'-Phosphopantetheinyl Transferase PptT, a new drug target required for mycobacterium tuberculosis growth and persistence in vivo One third of the world is infected with the bacterium that causes tuberculosis (TB), a disease that is increasingly difficult to treat because of wide spread resistance to available drugs. Researchers from the Institute of Pharmacology and Structural Biology (CNRS, Université de Toulouse) in Toulouse (France) have identified a fresh target to develop new drugs...
Latest Bacteria Reference Libraries
Yersinia enterocolitica is a species of gram-negative coccobacillus-shaped bacterium, belonging to the family Enterobacteriaceae. Infection from Yersinia enterocolitica causes the zoonotic disease yersiniosis. Most infected animals recover from the disease and become asymptomatic carriers. Acute infections lead to mild self-limiting entero-colitis or terminal ileitis in humans. Symptoms include watery or bloody diarrhea and fever. After oral uptake it replicates in the terminal ileum and...
Vibrio vulnificus is a species of Gram-negative, motile, curved, rod-shaped bacteria of the Vibrio Genus. Hollis et al. first reported it in 1976. It was given the name Beneckea vulnifica by Reichelt et al. in 1976 and in 1979 Vibrio vulnificus by Farmer. V. vulnificus is related to V. cholerae and is present in marine environments such as estuaries, brackish ponds, or coastal areas. It causes an infection often incurred after eating seafood, especially raw or undercooked oysters. It can...
Streptococcus mutans is a Gram-positive cocci, Facultative anaerobic bacterium commonly found in the human oral cavity and is a significant contributor to tooth decay. J Kilian Clarke first described the microbe in 1924. The first colonizers of the tooth surface are mainly Neisseria spp. and streptococci, including S. mutans. The pioneer species changes the local environmental conditions through growth and metabolism thus allowing more fastidious organisms to further colonize after them,...
Staphylococcus epidermidis is one of thirty-three known species belonging to the genus Staphylococcus. It is part of our skin flora and can also be found in the mucous membranes and in animals. It is the most common species found in laboratory test due to contamination. It is not usually pathogenic; however, patients with a compromised immune system often risk infection. Infections can be both nosocomial and community acquired and are more of a threat to hospital patients. Hospitals carry...
Staphylococcus aureus is a facultative anaerobic gram-positive coccus, and is the most common cause of staph infections. It is commonly part of the skin flora found in the nose and on skin. Around 20% of the human population is long-term carriers. It gets its golden color due to its carotenoid pigment staphyloxanthin. The pigment acts as a virulence factor with an antioxidant action that allows the microbe to evade death by reactive oxygen species used by the host immune system. Staphylococci...
