Latest Base pair Stories
A research team from NPL and the University of Edinburgh have invented a new way to zip and unzip DNA strands using electrochemistry.
When a proton – the bare nucleus of a hydrogen atom – transfers from one molecule to another, or moves within a molecule, the result is a hydrogen bond, in which the proton and another atom like nitrogen or oxygen share electrons.
DNA, that marvelous, twisty molecule of life, has an alter ego.
Molecular gauge to disclose function of new medications.
Scientists at the Georgia Institute of Technology have discovered that small molecules could have acted as "molecular midwives" in helping the building blocks of life's genetic material form long chains and may have assisted in selecting the base pairs of the DNA double helix.
A team of bioinformaticians at the UniversitÃ© de MontrÃ©al (UdeM) report in the March 6th edition of Nature the discovery of a structural alphabet that can be used to infer the 3D structure of ribonucleic acid (RNA) from sequence data, providing new tools to understand the role of this important class of cellular regulators.
Researchers at Stanford University have created a larger-than-normal DNA molecule that is copied almost as efficiently as natural DNA. The findings, reported in the Oct. 25 online edition of the Proceedings of the National Academy of Sciences (PNAS), may reveal new insights into how genetic mutations-tiny mistakes that occur during DNA replication-arise. The discovery was made in the laboratory of Eric Kool, a professor of chemistry at Stanford and co-author of the PNAS study.
For the first time, a team of investigators at Carnegie Mellon University has shown that the binding of metal ions can mediate the formation of peptide nucleic acid (PNA) duplexes from single strands of PNA that are only partly complementary. This result opens new opportunities to create functional, three-dimensional nanosize structures such as molecular-scale electronic circuits, which could reduce by thousands of times the size of today's common electronic devices. The research results will...
Chemists at Ohio State University have gained new insight into how sunlight affects DNA. And what they found overturns ideas about genetic mutation that originated decades ago.
Chemists at Ohio State University have gained new insight into how sunlight affects DNA. And what they found overturns ideas about genetic mutation that originated decades ago. In the current issue of the journal Nature, Bern Kohler and his colleagues report that DNA dissipates the energy from ultraviolet (UV) radiation in a kind of energy wave that travels up the edge of the DNA molecule, as if the energy were climbing one side of the helical DNA "ladder."
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