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Latest Beta amyloid Stories

2014-01-20 12:26:21

Study uncovers role of Neuroligin-1 protein Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today. The protein – Neuroligin-1 (NLGN1) – is known to be involved in memory formation; this is the first time it's been linked to amyloid-associated memory loss. In Alzheimer's disease, amyloid beta...

2014-01-16 23:27:40

Study indicates potential for TauC3 to be disease-modifying. Englewood Cliffs, New Jersey (PRWEB) January 16, 2014 Intellect Neurosciences, Inc. (OTCBB:ILNS), a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic and diagnostic agents for the treatment of Alzheimer's and other neurological diseases, today announced it obtained proof of concept in a preclinical Alzheimer's model for its TauC3 monoclonal antibody indicating its...

2014-01-13 10:21:10

New Study Pinpoints Structural Effects of V44M and V44A Mutations New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. In a paper published January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations – V44M and V44A – known to cause FAD,...

2014-01-06 10:17:40

Earlier amyloid-beta assemblies may be one of the most important causes of Alzheimer's disease. Passive immunization of anti-amyloid-beta antibodies can reduce amyloid-beta burden and improved memory performance in various Alzheimer's disease animal models or patients. Screening humanized antibodies from a human Fab phage display library is an effective and quick method to obtain beta-amyloid oligomers. Thus, a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013)...

2013-12-16 18:13:17

Massive neuron death that occurs in Alzheimer's appears to be caused by raw ingredients of plaques & tangles working in concert, rather than by plaques and tangles themselves Much of the debate in Alzheimer's disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease. But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two...

Study Suggests Brain Blood Vessel Cells May Be Therapeutic Targets For Alzheimer's Disease
2013-12-13 14:28:51

NIH/National Institute of Neurological Disorders and Stroke A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses. "This study helps show how the brain's vascular system may contribute to the development of Alzheimer's disease," said study leader Berislav V....

2013-12-03 23:02:00

St. Jude Children’s Research Hospital scientists identify enzyme that could lead to better diagnosis and treatment of Alzheimer’s disease and related disorders. Memphis, Tenn. (PRWEB) December 03, 2013 St. Jude Children’s Research Hospital scientists have identified an enzyme that can halt or possibly even reverse the build-up of toxic protein fragments known as plaques in the brains of mice with Alzheimer’s disease. The research appeared in a recent edition of the scientific...

2013-11-11 21:27:19

Patients with traumatic brain injury (TBI) had increased deposits of β-Amyloid (Aβ) plaques, a hallmark of Alzheimer Disease (AD), in some areas of their brains in a study by Young T. Hong, Ph.D., of the University of Cambridge, England, and colleagues. There may be epidemiological or pathophysiological (changes because of injury) links between TBI and AD, and Aβ plaques are found in as many as 30 percent of patients who die in the acute phase after a TBI. The plaques appear within...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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