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Unraveling Mysteries Of Amyloid Beta Peptides To Detect And Treat Alzheimer's Disease
2014-02-18 07:41:38

American Institute of Physics Alzheimer's disease has long been marked by progress -- but not the kind of progress the medical community seeks. It is the most common form of dementia among older Americans, and its risk increases with increasing age; for those living with the disease, its ravages get worse over time; and as we move into the 21st century, it will place a greater and greater burden on society. The number of Americans living with Alzheimer's has doubled since 1980 and is...

2014-02-12 12:30:19

Eli Lilly, the Sole Competitor in 2013, Will Be Joined by GE Healthcare, Piramal Enterprises and Navidea Biopharmaceuticals in the Next Few Years, According to Findings from Decision Resources Group BURLINGTON, Mass., Feb. 12, 2014 /PRNewswire/ -- Decision Resources Group finds that the United States Alzheimer's imaging agent market will grow dramatically over the next 10 years. Currently, Eli Lilly's Amyvid, launched in June 2013, is the only Food and Drug Administration...

2014-01-22 10:56:45

Alzheimer's disease can reach epidemic range in the coming decades, by the increasing average age of society.There are two key issues for Alzheimer's disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies. Alzheimer's disease Pathologically, Alzheimer's disease is characterized by the accumulation of protein deposits in the brain of patients. These deposits are...

2014-01-22 08:29:18

TSX: AMF TORONTO, Jan. 22, 2014 /CNW/ - Amorfix Life Sciences Ltd. announced today that the Company has signed an agreement with a major global pharmaceutical company to use the human Alzheimer's disease diagnostic assay in phase 1 clinical studies. Amorfix has granted its collaborator access to its proprietary EP-AD assay technology and the Company will complete assay optimization and validation prior to using the assay as part of a clinical trial to investigate the effects...

2014-01-20 12:26:21

Study uncovers role of Neuroligin-1 protein Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today. The protein – Neuroligin-1 (NLGN1) – is known to be involved in memory formation; this is the first time it's been linked to amyloid-associated memory loss. In Alzheimer's disease, amyloid beta...

2014-01-16 23:27:40

Study indicates potential for TauC3 to be disease-modifying. Englewood Cliffs, New Jersey (PRWEB) January 16, 2014 Intellect Neurosciences, Inc. (OTCBB:ILNS), a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic and diagnostic agents for the treatment of Alzheimer's and other neurological diseases, today announced it obtained proof of concept in a preclinical Alzheimer's model for its TauC3 monoclonal antibody indicating its...

2014-01-13 10:21:10

New Study Pinpoints Structural Effects of V44M and V44A Mutations New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. In a paper published January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations – V44M and V44A – known to cause FAD,...

2014-01-06 10:17:40

Earlier amyloid-beta assemblies may be one of the most important causes of Alzheimer's disease. Passive immunization of anti-amyloid-beta antibodies can reduce amyloid-beta burden and improved memory performance in various Alzheimer's disease animal models or patients. Screening humanized antibodies from a human Fab phage display library is an effective and quick method to obtain beta-amyloid oligomers. Thus, a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013)...

2013-12-16 18:13:17

Massive neuron death that occurs in Alzheimer's appears to be caused by raw ingredients of plaques & tangles working in concert, rather than by plaques and tangles themselves Much of the debate in Alzheimer's disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease. But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two...

Study Suggests Brain Blood Vessel Cells May Be Therapeutic Targets For Alzheimer's Disease
2013-12-13 14:28:51

NIH/National Institute of Neurological Disorders and Stroke A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses. "This study helps show how the brain's vascular system may contribute to the development of Alzheimer's disease," said study leader Berislav V....


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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