Latest Beta amyloid Stories
UC Davis researchers have found novel compounds that disrupt the formation of amyloid, the clumps of protein in the brains of people with Alzheimer's disease believed to be important in causing the disease's characteristic mental decline. The so-called "spin-labeled fluorene compounds" are an important new target for researchers and physicians focused on diagnosing, treating and studying the disease. The study, published today in the online journal PLoS ONE, is entitled "The influence of...
NEW ORLEANS, April 25, 2012 /PRNewswire/ -- Results of a phase III study that showed tremendous reliability in the detection of beta-amyloid in the living brain will be presented by Marwan Sabbagh, MD, director of Banner Sun Health Research Institute in Sun City Arizona. The presentation is part of the Emerging Science Program on April 25th at the American Academy of Neurology's 64th Annual meeting in New Orleans. Historically, Alzheimer's disease has only been definitively...
Without p-tau protein present, impact of amyloid is 'not significantly different from zero' According to a new study, the neuron-killing pathology of Alzheimer's disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau. Without both, progressive clinical decline associated with AD in cognitively healthy older individuals is "not significantly different from...
NEW YORK, April 23, 2012 /PRNewswire/ -- Oligomerix, Inc., a privately held company pioneering the development of disease modifying therapeutics for Alzheimer's disease and related neurodegenerative disorders, announced today the completion of approximately $2 million in Series A financing, which includes both issuance of new convertible preferred shares and debt conversion. Wheatley MedTech Partners, L.P., Wheatley New York Partners LP and Durand Venture Associates, LLC were the...
Multiple disease-related changes progress in parallel through distinct stages Studying a mouse model of Alzheimer's disease, neuroscientists at the Technische Universitaet Muenchen have observed correlations between increases in both soluble and plaque-forming beta-amyloid – a protein implicated in the disease process – and dysfunctional developments on several levels: individual cortical neurons, neuronal circuits, sensory cognition, and behavior. Their results, published in Nature...
NEW YORK, April 17, 2012 /PRNewswire/ -- Intellect Neurosciences, Inc. (OTCBB:ILNS), a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic agents for the treatment of Alzheimer's and other neurological diseases today announced it has entered into a collaboration agreement with the University California, Irvine to test RV03 a preclinical, first-in-class, dual acting peptide vaccine candidate to induce an immune response against beta...
(Ivanhoe Newswire)-- Having a loved one diagnosed with Alzheimer's disease can be devastating, especially without warning. Now a recent study shows how doctors may be able to diagnose the disease earlier. Early detection would give more time for family members to prepare for the devastating disease. Currently, Alzheimer's disease can only be definitively confirmed through the detection of amyloid plaques and/or tangles in the brain during autopsy after death or with a brain tissue...
Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. Currently, Alzheimer's disease can only be definitively confirmed through the detection of amyloid...
NEW ORLEANS, April 15, 2012 /PRNewswire-USNewswire/ -- Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. Currently, Alzheimer's disease can only be...
MUMBAI, India, April 15, 2012 /PRNewswire/ -- Piramal Healthcare Limited [NSE: PIRHEALTH, BSE: 500302] ("Piramal"), announced that it has signed an agreement to acquire worldwide rights to the molecular imaging research and development portfolio of Bayer Pharma AG ("Bayer") through its newly created subsidiary - Piramal Imaging SA. The portfolio includes rights to florbetaben, which is in the final stages of its Phase III clinical trials. First Phase III results will be...
