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Latest Beta cell Stories

2011-09-07 12:33:30

Mysterious mesenchyme is key piece of pancreatic puzzle A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body's insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes. As reported today in the journal PLoS Biology, during the late stages...

2011-09-06 22:32:12

JDRF-funded scientists collaborate with pharmaceutical company to uncover new ways to stimulate pancreatic beta cell growth One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates...

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2011-08-15 05:15:00

Obesity and type 2 diabetes have long been linked, but a new study has discovered exactly how high-fat diets serve as a catalyst for a sequence of events that ultimately lead to the onset of the disease. Researchers, including Jamey D. Marth, Ph.D., the director of the Center for Nanomedicine, studied both humans and mice, and "discovered a pathway to disease that is activated in pancreatic beta cells, and then leads to metabolic defects in other organs and tissues, including the liver,...

2011-08-09 14:58:21

A newly-identified protein may hold the key to keeping appetite and blood sugar in check, according to a study by York University researchers. Suraj Unniappan, associate professor in York's Department of Biology, Faculty of Science & Engineering, is delving into the metabolic effects of a protein called nesfatin-1, abundantly present in the brain. His studies found that rats administered with nesfatin-1 ate less, used more stored fat and became more active. In addition, the protein...

2011-07-13 23:25:15

Adult-derived stem cells could pave the way for new treatment of diabetes, says TAU researcher Stem cells from early embryos can be coaxed into becoming a diverse array of specialized cells to revive and repair different areas of the body. Therapies based on these stem cells have long been contemplated for the treatment of diabetes, but have been held back by medical and ethical drawbacks. Now researchers at Tel Aviv University are capitalizing on the "memories" of stem cells generated from...

2011-07-01 13:08:50

In type 2 diabetes, a protein called amylin forms dense clumps that shut down insulin-producing cells, wreaking havoc on the control of blood sugar. But zinc has a knack for preventing amylin from misbehaving. Recent research at the University of Michigan offers new details about how zinc performs this "security guard" function. The findings appear in the July 8 issue of the Journal of Molecular Biology. Amylin is something of a two-faced character. In healthy people who have normal levels of...

2011-06-29 12:11:21

A chemical produced by the same cells that make insulin in the pancreas prevented and even reversed Type 1 diabetes in mice, researchers at St. Michael's Hospital have found. Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's destruction of the beta cells in the pancreas that make and secrete insulin. As a result, the body makes little or no insulin. The only conventional treatment for Type 1 diabetes is insulin injection, but insulin is not a cure...

2011-06-27 09:24:00

ROCKVILLE, Md., June 27, 2011 /PRNewswire-USNewswire/ -- Results of two studies testing drugs to slow or stop the immune system's attack on insulin-producing cells in people newly diagnosed with type 1 diabetes will be presented at the American Diabetes Association's (ADA) 71st Scientific Sessions in San Diego and simultaneously published online in the Lancet. The studies were conducted by the National Institutes of Health's international network of researchers, Type 1 Diabetes TrialNet...

2011-06-24 16:00:00

LA JOLLA, Calif., June 24, 2011 /PRNewswire/ -- Cebix Incorporated announced today that preclinical data for its long-acting form of C-peptide, Ersatta(TM) (CBX129801), demonstrated a half-life of three days as compared to one hour for native C-peptide. Ersatta halted the impairment in nerve conduction velocity, a measure of the rate at which electrical signals travel through the nerves, in an animal model of diabetic peripheral neuropathy. Additionally, clinical data showed that native...


Latest Beta cell Reference Libraries

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2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

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Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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