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Latest Beta cell Stories

2011-01-27 15:26:34

Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest. These findings in mice show that insulin becomes completely superfluous and its absence does not cause diabetes or any other abnormality when the actions of glucagon are suppressed. Glucagon, a hormone produced by the pancreas, prevents low blood sugar levels in healthy individuals. It causes...

2011-01-04 13:30:32

The research group led by professor Makoto Tominaga and Dr. Kunitoshi Uchida, National institute for Physiological Sciences (NIPS), found TRPM2 ion channel in pancreatic beta-cells is important for insulin secretion stimulated by glucose and gastrointestinal hormone (incretin) secreted after food intake.  Their finding was reported in Diabetes. Diabetes mellitus is a disease caused by lack of insulin secretion from pancreatic cells, or less response to the secreted insulin, which raises...

2010-12-27 13:43:25

New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called "starvation hormone" affects multiple biological systems, including preventing insulin sensitivity and promoting cell survival. The results connect multiple observations about how the hormone adiponectin functions and eventually could lead to new treatments for conditions ranging from diabetes and weight loss to heart disease and cancer. "Until now, there wasn't really an obvious...

2010-12-09 14:24:14

Team finds new software accurately predicts key information on nasal insulin treatment A La Jolla Institute team, led by leading type 1 diabetes researcher Matthias von Herrath, M.D., has demonstrated the effectiveness of a recently developed computer model in predicting key information about nasal insulin treatment regimens in type 1 (juvenile) diabetes. Development of the software, the Type 1 Diabetes PhysioLab® Platform, was funded through the peer-reviewed grant program...

2010-11-02 07:30:00

CAMBRIDGE, Mass., Nov. 2 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company developing novel therapies to treat autoimmune diseases and cancer by modulating T cell activity, announced today that it has established a Scientific Advisory Board to help advance the company's research and clinical studies in type 1 diabetes. This Scientific Advisory Board will support the scientific advancements that underlie the company's lead drug candidate, otelixizumab, as well as guide the creation...

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2010-10-28 14:19:46

Anne M Stark, Lawrence Livermore National Laboratory Beta cells, which make insulin in the human body, do not replicate after the age of 30, indicating that clinicians may be closer to better treating diabetes. Type 1 diabetes is caused by a loss of beta cells by auto-immunity while type 2 is due to a relative insufficiency of beta cells. Whether beta cells replicate after birth has remained an open issue, and is critically important for designing therapies for diabetes. By using radioactive...

2010-10-12 17:26:57

Mutant gene protein can derail normal insulin production in animal pancreatic beta cells University of Michigan scientists have identified events inside insulin-producing pancreatic cells that set the stage for a neonatal form of non-autoimmune type 1 diabetes, and may play a role in type 2 diabetes as well. The results point to a potential target for drugs to protect normally functioning proteins essential for producing insulin. A study published online today in the journal PLoS One shows...

2010-10-06 23:11:17

Endocrine Society launches website for primary care physicians on applying new insights into the role of beta-cells in type 2 diabetes to clinical practice A new consensus statement published in the September, 2010, issue of The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) finds that the increasing recognition that beta-cell failure occurs much earlier and severely than commonly believed suggests that regular glycemia screening, early identification of...

2010-09-29 12:38:00

GORDONSVILLE, Va., Sept. 29 /PRNewswire/ -- Some of the leading experts in the field of Diabetes research will gather in Charlottesville this week for the first annual Manning Diabetes Symposium at the University of Virginia. The event is named for entrepreneur Paul Manning and his wife Diane Manning, whose foundation, The Focus to Cure Diabetes Foundation, and extraordinary commitment to the battle against the disease has seen the couple donate more than $5 million to diabetes research...

2010-09-28 20:55:06

Crowdsourcing, the act of contracting out problems to large groups rather than tapping individual experts, has solved puzzles in fields such as marketing, engineering and computer software. But can the wisdom of crowds help cure disease? A large, multidisciplinary panel has recently selected 12 pioneering ideas for attacking Type 1 Diabetes, ideas selected through a crowdsourcing experiment called the Challenge in which all members of the Harvard community, as well as members of the general...


Latest Beta cell Reference Libraries

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2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

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Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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