Quantcast

Latest Beta cell Stories

2009-10-08 09:18:04

One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. A team from the Children's Hospital of Eastern Ontario (CHEO) Research Institute has identified a protein that inhibits insulin production in mice - work that offers a new way of understanding, and perhaps of one day treating, both Type 1 and Type 2 diabetes. A study to be published today in the leading international journal...

2009-09-10 15:04:00

MINNEAPOLIS, Sept. 10 /PRNewswire/ -- Exsulin Corporation today announced the start of a phase II human clinical trial of Exsulin(TM), a peptide drug product aimed at restoring insulin production in people with diabetes mellitus. The randomized, controlled 12-week trial in patients with established Type 1 diabetes (T1DM) will be co-led by Mayo Clinic in Rochester, Minn., and McGill University Health Centre in Montreal, Canada. First results are expected to be available in Q2 2010. The...

2009-09-09 12:30:00

WYNNEWOOD, Pa., Sept. 9 /PRNewswire/ -- CureDM, Inc., a biopharmaceutical company dedicated to developing novel therapeutic approaches to Diabetes Mellitus, announced today that CureDM has been chosen as the recipient of Frost and Sullivan's Technology Innovation Award for 2009 for its development of Pancreate(TM), a human peptide therapeutic. The 2009 North American Diabetes Mellitus Therapeutics Excellence in Healthcare Product Innovation of the Year Award is bestowed upon a company that...

2009-09-08 14:35:13

Scientists from Canada, France, the United Kingdom and Denmark say they have identified a new gene involved in type 2 diabetes. The scientists said the gene, called Insulin Receptor Substrate 1, causes resistance to insulin and is the first gene known to affect how insulin works, not how it is produced. The researchers said their discovery could lead to better treatment of type 2 diabetes, as well as a better understanding of how the widespread disease develops. Most of the genes that we've...

2009-09-08 14:38:13

By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias. The findings, which appear this week in the Early Edition of the Proceedings of the National Academy of Sciences, may help identify new molecular targets for...

293355c0ace8784b314d391f1d6d5f12
2009-09-07 07:35:00

Discovery is first gene known to affect how insulin works, not how it is produced A breakthrough by an international team of researchers in Canada, France, the UK and Denmark has uncovered a new gene that could lead to better treatment of type 2 diabetes, as well as a better understanding of how this widespread disease develops. Unlike most of the genes that have been shown to cause diabetes, the new gene, called Insulin Receptor Substrate 1 (IRS1), doesn't affect how insulin is created in...

2009-08-18 09:48:00

MINNEAPOLIS, Aug. 18 /PRNewswire/ -- Exsulin Corporation today announced milestones achieved and immediate plans to move forward as a well supported Minnesota-based company dedicated to the development of regeneration therapies for the treatment of diabetes mellitus. Exsulin's focus is on development of a drug with potential to become a breakthrough therapy for patients suffering from type 1 (T1DM) and type 2 diabetes (T2DM). Phase II human clinical trial data of Exsulin(TM) (INGAP...

2009-08-11 07:05:00

CAMBRIDGE, Mass., Aug. 11 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for immune-mediated diseases, today announced changes to the protocol for its Phase 3 clinical trial DEFEND, which is testing the safety and efficacy of otelixizumab, a targeted T cell immunomodulator, in patients with new-onset autoimmune type 1 diabetes. The DEFEND (Durable Response Therapy Evaluation For Early or New-Onset Type 1 Diabetes)...

2009-08-06 13:30:16

Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal.When the gene called Pax4 is forced on in pancreatic alpha cells, the cells change their identity to become beta cells, the researchers found. The body in turn senses a loss of alpha cells,...

2009-08-06 00:28:31

Physicians may be able to use magnetic resonance imaging to help early diagnosis, staging and treatment of diabetes, U.S. researchers said. Researchers at Massachusetts General Hospital and Harvard Medical School in Boston said with the non-invasive MRI, physicians would have the ability to evaluate beta cell mass, a major factor of insulin secretion that is significantly reduced in type 2 diabetes and almost gone in type 1 diabetes. We are also able to detect inflammation of the pancreas and...


Latest Beta cell Reference Libraries

0_0d961f30bdfa64859d9b869b063ddcd2
2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

More Articles (1 articles) »
Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.