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Latest Beta cell Stories

2009-09-08 14:35:13

Scientists from Canada, France, the United Kingdom and Denmark say they have identified a new gene involved in type 2 diabetes. The scientists said the gene, called Insulin Receptor Substrate 1, causes resistance to insulin and is the first gene known to affect how insulin works, not how it is produced. The researchers said their discovery could lead to better treatment of type 2 diabetes, as well as a better understanding of how the widespread disease develops. Most of the genes that we've...

2009-09-08 14:38:13

By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias. The findings, which appear this week in the Early Edition of the Proceedings of the National Academy of Sciences, may help identify new molecular targets for...

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2009-09-07 07:35:00

Discovery is first gene known to affect how insulin works, not how it is produced A breakthrough by an international team of researchers in Canada, France, the UK and Denmark has uncovered a new gene that could lead to better treatment of type 2 diabetes, as well as a better understanding of how this widespread disease develops. Unlike most of the genes that have been shown to cause diabetes, the new gene, called Insulin Receptor Substrate 1 (IRS1), doesn't affect how insulin is created in...

2009-08-18 09:48:00

MINNEAPOLIS, Aug. 18 /PRNewswire/ -- Exsulin Corporation today announced milestones achieved and immediate plans to move forward as a well supported Minnesota-based company dedicated to the development of regeneration therapies for the treatment of diabetes mellitus. Exsulin's focus is on development of a drug with potential to become a breakthrough therapy for patients suffering from type 1 (T1DM) and type 2 diabetes (T2DM). Phase II human clinical trial data of Exsulin(TM) (INGAP...

2009-08-11 07:05:00

CAMBRIDGE, Mass., Aug. 11 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for immune-mediated diseases, today announced changes to the protocol for its Phase 3 clinical trial DEFEND, which is testing the safety and efficacy of otelixizumab, a targeted T cell immunomodulator, in patients with new-onset autoimmune type 1 diabetes. The DEFEND (Durable Response Therapy Evaluation For Early or New-Onset Type 1 Diabetes)...

2009-08-06 13:30:16

Researchers have found a way in mice to convert another type of pancreas cell into the critical insulin-producing beta cells that are lost in those with type I diabetes. The secret ingredient is a single transcription factor, according to the report in the August 7th issue of Cell, a Cell Press journal.When the gene called Pax4 is forced on in pancreatic alpha cells, the cells change their identity to become beta cells, the researchers found. The body in turn senses a loss of alpha cells,...

2009-08-06 00:28:31

Physicians may be able to use magnetic resonance imaging to help early diagnosis, staging and treatment of diabetes, U.S. researchers said. Researchers at Massachusetts General Hospital and Harvard Medical School in Boston said with the non-invasive MRI, physicians would have the ability to evaluate beta cell mass, a major factor of insulin secretion that is significantly reduced in type 2 diabetes and almost gone in type 1 diabetes. We are also able to detect inflammation of the pancreas and...

2009-08-05 09:59:08

Noninvasive imaging (MRI) may aid physicians in the early diagnosis, staging and treatment of diabetes, according to a study performed at Massachusetts General Hospital and Harvard Medical School in Boston, MA. This is the first study of its kind to apply noninvasive imaging techniques to diabetes research."With noninvasive MRI we have the ability to evaluate beta cell mass, a major factor of insulin secretion that is significantly reduced in type two diabetes and almost gone in type one,"...

2009-07-21 20:20:00

In the new issue of the Developmental Cell journal, a team of scientists at Singapore's Agency for Science, Technology and Research (A*STAR) and the University of North Carolina School of Medicine at Chapel Hill, report research findings about the molecular mechanisms behind the aging process, which has up till now been poorly understood, that offer the possibility that a novel, pharmacological approach could be developed to combat age-related disorders.In their research with lab rodents, the...

2009-07-21 13:08:47

Pancreatic cells that pump insulin also produce a destructive substance that can kill the cells that produced it, U.S. scientists studying diabetes said. The destructive protein creates a perfect storm for the development of Type 2 diabetes, Dr. Franco Folli of the University of Texas Health Science Center said. You have a condition in which the beta cells die and the alpha cells proliferate. This is the balance that is basically necessary to have the onset of Type 2 diabetes, Folli said in...


Latest Beta cell Reference Libraries

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2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

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Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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