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Latest Beta cell Stories

2012-02-21 23:12:34

C-peptide production and beta cell functioning detected decades after disease onset Massachusetts General Hospital (MGH) research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent loss of pancreatic function. "Traditionally, it was thought that beta cell function completely ceased in patients with advanced type 1 diabetes. However, data from this study and...

2012-02-17 00:38:02

Scientists have taken a remarkably detailed look at the initial steps that occur in the body when type 1 diabetes mellitus first develops in a child or young adult. The analysis comes from a team of researchers and physicians at the University of Rochester Medical Center who have expertise both in the laboratory and in treating patients. The team studied children from ages 8 to 18 within 48 hours of their diagnosis with type 1 diabetes, an autoimmune disease where the body´s immune...

2012-02-06 22:38:00

Sanford-Burnham researchers discover taste receptors in pancreatic beta cells that can sense fructose and stimulate insulin secretion Taste receptors on the tongue help us distinguish between safe food and food that's spoiled or toxic. But taste receptors are now being found in other organs, too. In a study published online the week of February 6 by the Proceedings of the National Academy of Sciences of the USA, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham)...

2012-02-02 07:51:11

The development of a medicine for patients with type 1 diabetes mellitus, based on autoantigen GAD65, received a setback following crucial clinical phase 3 trials that failed to show significant effects. One possible explanation may be seasonal variations in the immune system, claim those responsible for the study that was published in the New England Journal of Medicine (NEJM). At the onset of type 1 diabetes mellitus, the immune system attacks the insulin-producing pancreatic beta-cells....

2012-01-23 11:33:00

PRINCETON, N.J., Jan. 23, 2012 /PRNewswire/ -- Novo Nordisk (NYSE:NVO) announced today that the company will establish a type 1 diabetes research and development center in Seattle, Wash., U.S. The new center will combine Novo Nordisk's history of innovation and leadership in diabetes treatment with the company's growing expertise in immunotherapy. "Novo Nordisk has been passionate about helping people fight diabetes since the company was founded, and it is part of our mission to...

2012-01-19 06:21:24

(Ivanhoe Newswire) -- Killer T-cells protect the body from disease, but a new study suggests that these same cells, created to protect, may be inadvertently destroying cells that produce insulin for the body. Professor Andy Sewell, an expert in human T-cells from Cardiff University´s School of Medicine and his diabetic expert colleagues, among them Professor Mark Peakman from the National Institute for Health Research (NIHR) Biomedical Research Centre at King´s College and...

2012-01-16 10:49:28

Killer T-cells in the human body which help protect us from disease can inadvertently destroy cells that produce insulin, new research has uncovered. The study provides the first evidence of this mechanism in action and could offer new understanding of the cause of Type 1 diabetes. Professor Andy Sewell, an expert in human T-cells from Cardiff University's School of Medicine worked alongside diabetes experts from King's College London to better understand the role of T-cells in the...

2012-01-16 07:30:00

LAGUNA HILLS, Calif., Jan. 16, 2012 /PRNewswire/ -- LoneStar Heart Inc., based here, today announced that it has acquired a worldwide exclusive license from the University of Texas Southwestern Medical Center (UT Southwestern) to commercialize a new class of patented small molecules known as Isoxazoles that markedly increase insulin production in human pancreas cells no longer able to produce insulin. Activating the entire biochemical pathway involved in insulin production,...

2012-01-13 06:51:32

(Ivanhoe Newswire)- Type 1 diabetes is caused by the body's own immune system attacking its pancreatic islet beta cells and requires daily injections of insulin to regulate the patient's blood glucose levels. A new method found in the BioMed Central's open access journal BMC Medicine uses stem cells from cord blood to reeducate the T cells in a diabetic's blood to restart the pancreatic function and reduce the need for insulin. In Stem Cell Educator therapy, lymphocytes were separated from...

2012-01-12 14:39:04

JDRF's organ donation network key in research findings Researchers at the La Jolla Institute for Allergy & Immunology have proven — for the first time in human tissues -- the specific immune system T cells which trigger the destruction of type 1 diabetes in the pancreas. The finding is an important advance that verifies in humans several important disease characteristics shown in mouse studies and provides a key focal point for interrupting the disease process. "This study...


Latest Beta cell Reference Libraries

0_0d961f30bdfa64859d9b869b063ddcd2
2010-12-03 18:12:26

Insulin, a hormone, is used to regulate carbohydrate and fat metabolism in the body. Insulin causes cells to take up glucose from the blood and store it as glycogen in the liver and muscle. This hormone stops the body from using fat as an energy source by inhibiting the release of glucagons. Without insulin the body fails to take glucose into the bodies cells and in turns uses fat as an energy source. It also has several other anabolic effects throughout the body. Diabetes mellitus results...

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