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Latest Beta secretase Stories

2011-02-04 11:23:44

Finding could lead to novel drugs that prevent or slow the disease Like two unruly boys who need to be split up in class, a pair of protein molecules work together to speed up the toxic events of Alzheimer's disease. Researchers at the UT Health Science Center San Antonio today announced the discovery of the second molecule and said its identification could lead to drugs that disrupt the interaction, and thereby block or slow Alzheimer's onset or progression. Alzheimer's disease is an...

2010-12-02 23:45:40

Study Highlights:     * A blood vessel dysfunction linked to cardiovascular disease seems to also play a role in Alzheimer's disease.    * The dysfunction may help account for the buildup of amyloid plaques in the brains of Alzheimer's patients. A dysfunction in the lining of blood vessels that is linked to cardiovascular illness also appears to play a role in the development of Alzheimer's disease, according to a study published in Circulation Research: Journal...

2010-12-02 16:35:00

DALLAS, Dec. 2, 2010 /PRNewswire-USNewswire/ -- A dysfunction in the lining of blood vessels that is linked to cardiovascular illness also appears to play a role in the development of Alzheimer's disease, according to a study published in Circulation Research: Journal of the American Heart Association. (Logo: http://photos.prnewswire.com/prnh/20100222/AHSALOGO) Alzheimer's disease is a progressive brain condition that typically affects people age 60 and older, depriving them of memory,...

2010-11-18 14:40:30

Asthma inhibitors could help control or treat the disease A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine. The researchers also found that inhibitors of this protein currently used to control asthma could possibly be...

2010-10-13 13:29:56

Stimulating the brain's Alpha7 nicotine receptor may eliminate side effects caused by promising Alzheimer's drug A team of neuroscientists has discovered important new information in the search for an effective treatment for Alzheimer's disease, the debilitating neurological disorder that afflicts more than 5.3 million Americans and is the sixth-leading cause of death in the United States. Hey-Kyoung Lee, associate professor in the University of Maryland Department of Biology, and her...

2010-10-12 18:38:00

Mount Sinai School of Medicine researchers have found that a gene associated with the onset of Type 2 diabetes also is found at lower-than-normal levels in people with Alzheimer's disease. The research, led by Giulio Maria Pasinetti, MD, PhD, The Saunder Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this month in Aging Cell. The new study provides insight into a potential mechanism that might...

2010-06-18 12:58:12

The first trial of a new model for testing Alzheimer's treatments has reassured researchers that a promising class of drugs does not exacerbate the disease if treatment is interrupted. Scientists at Washington University School of Medicine in St. Louis and Merck & Co. Inc studied the effects of a class of drugs known as gamma secretase inhibitors. Researchers had worried that these drugs might cause a build-up of proteins linked to Alzheimer's disease and that this build-up could be...

2010-06-11 01:45:50

Findings could pave the way for novel treatments Researchers have discovered how mutations in the presenilin 1 gene cause early-onset Alzheimer's disease (AD). The finding, reported online in the journal Cell, opens the door to developing novel treatments for this form of the mind-robbing disease and for the more common, late-onset form that develops later in life and affects millions of people worldwide. The presenilin gene is most commonly associated with the early-onset familial form of...

2010-05-25 13:40:32

Researchers at Tufts University School of Medicine have zeroed in on a protein that may play a role in the progression of Alzheimer's disease. The team found that increasing levels of the protein (called GGA3) prevented the accumulation of an enzyme linked to Alzheimer's. The strategy may lead to new treatments for the neurodegenerative disease. The findings were published online May 18 in the Journal of Biological Chemistry. People with Alzheimer's disease typically have higher levels of an...

2009-09-28 00:59:07

U.S. researchers say they are testing gammaglobulin as a treatment to help slow the progress of Alzheimer's disease. The study -- called the Gammaglobulin Alzheimer's Partnership Study -- is recruiting 360 participants at 36 sites nationwide. The large Phase III clinical trial expands on earlier testing and is part of the final phase before seeking regulatory approval for treating Alzheimer's disease with intravenous immune globulin or IGIV, also known as gammaglobulin -- a traditional...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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