Latest Beta secretase Stories

2008-07-28 09:00:31

CoMentis, Inc. and Astellas Pharma, Inc. announced today that the companies will present six abstracts related to CTS21166 (ASP1702), a beta-secretase inhibitor for the treatment of Alzheimer's disease, at the 2008 International Conference on Alzheimer's Disease (ICAD) in Chicago, July 26-31. CTS21166 (ASP1702) is the first of several highly selective, potent and orally active beta-secretase inhibitors being developed by CoMentis and Astellas. The following posters related to CTS21166...

2008-07-04 03:00:08

By Anonymous Study details new molecular approach to preventing Alzheimer's. The April 24 Washington Post reported that German researchers have developed a new approach to the possible prevention of the molecular "debris" that is associated with the development of Alzheimer's disease. The basic idea - to block the activity of an enzyme called beta secretase - is not original, says a new study's lead author. Both academic and commercial laboratories are working on methods to prevent the...

2008-04-25 00:05:00

German scientists say a new drug designed to attach itself to cells reversed signs of Alzheimer's disease when injected into the brains of mice and it could give hope to developing a new treatment for the condition in humans.The compound effectively blocks an enzyme responsible for the build-up of sticky deposits, or plaques, in the brain. The formation of plaque is thought to be one of the crucial factors in the development of Alzheimer's disease. The new drug attaches itself to exactly...

2005-09-20 15:55:39

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease. "What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already...

2005-06-20 18:40:00

The route to a treatment for Alzheimer's disease may have become more straightforward with the discovery that a key enzyme known to have a major role in this disease is in fact part of a family of enzymes. Only some family members play a role in the progression of this brain-wasting illness, new research at the University of Toronto has found. "It was previously thought that an enzyme called gamma-secretase contributed to the development of protein deposits in the Alzheimer's brain. This...

Word of the Day
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.