Latest Biliary atresia Stories
The lives of 39 children were saved with liver transplants by Texas Children's in 2012 HOUSTON, Jan. 31, 2013 /PRNewswire-USNewswire/ -- Texas Children's Hospital in Houston announced that in 2012 the hospital saved the lives of 39 children through liver transplantation, making it the most active pediatric liver transplant center in the nation and one of the most active in the world. To learn more about liver transplantation at Texas Children's Hospital please visit...
CHENGDU, China, May 25, 2012 /PRNewswire-Asia/ -- Recently, Wang Qiao, the eight-year program student of Liver and Vascular Surgery of West China Hospital tutored under Yan Lynan, went to San Francisco to attend the 18th ILTS (International Liver Transplantation Society) annual meeting with the director of his department, Mr. Li Bo. (Photo: http://photos.prnewswire.com/prnh/20120525/CN13960) The theme of the meeting is "The Pros and Cons Trade-Off for Liver Transplantation", and...
Results may have important implications for counseling parents on organ donation Children with a rare, life-threatening disease that is the most common cause of neonatal liver failure – biliary atresia – better tolerate liver transplants from their mothers than from their fathers, according to a UCSF-led study. In the study, researchers reviewed all pediatric liver transplants nationwide from 1996 to 2010, and compared the outcomes for patients who received liver grafts from their...
Unexpected discovery of a new molecular signature for a destructive and often lethal pediatric liver disease may lead to a new therapeutic target for the hard-to-treat condition. In a study that included human livers and a mouse model of biliary atresia, researchers report in the November Journal of Clinical Investigation that not all children with biliary atresia share the same disease process. Some patients have a second molecular conductor of disease called Th2 (T helper cell 2) immune...
CINCINNATI, Nov. 8, 2011 /PRNewswire-USNewswire/ -- Unexpected discovery of a new molecular signature for a destructive and often lethal pediatric liver disease may lead to a new therapeutic target for the hard-to-treat condition. (Logo: <font size="2" face="Arial">http://photos.prnewswire.com/prnh/20110406/MM79025LOGO</font>) In a study that included human livers and a mouse model of biliary atresia, researchers report in the November Journal of Clinical Investigation...
Biliary atresia (BA) is an inflammatory obliterative cholangiopathy with unknown etiology, leading to progressive fibrosis and cirrhosis. Microarray technology, emerged as an indispensable research tool for gene expression profiling, has been used to study the mechanism underlying BA, and allows the simultaneous analysis of thousands of transcripts within a single experiment. Some studies have been performed to investigate the gene expression profiling of livers from BA patients. However,...
CU School of Medicine researchers find link to infectionResearchers at the University of Colorado School of Medicine and The Children's Hospital have taken a big step toward understanding what causes one of the most serious liver diseases in infants.The disease is called biliary atresia, It blocks the bile ducts in young infants, through which bile, crucial for digestion, flows to the small intestine. The disease is rare "“ it strikes in about one in 10,000 births. But it's...
Researchers have identified a set of "molecular signatures" for biliary atresia "“ the most common diagnosis leading to liver transplant in children "“ that can help identify the progression of disease at diagnosis and predict clinical outcomes.The Cincinnati Children's Hospital Medical Center scientists found that using traditional methods to analyze liver biopsies, only 14 of 47 infants with biliary atresia could be identified as having either inflammation or fibrosis...
WASHINGTON and BOSTON, Oct. 27 /PRNewswire/ -- Commercially available multivitamin preparations commonly given to infants with biliary atresia to prevent fat soluble vitamin deficiencies are ineffective, according to researchers presenting at the 2009 annual meeting of the American Association for the Study of Liver Diseases. "This study examined a multivitamin preparation, which if often used by clinicians due to the convenience and perception that it is effective, however, there are...
Scientists have linked an overactive response by one of the immune system's key weapons against infection "“ natural killer, or NK, cells "“ to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe liver damage and death.Researchers at Cincinnati Children's Hospital Medical Center also report that blocking a gene that helps NK cells attack bile duct tissues lessens damage and may be a way to treat the most common cause of chronically progressive...
