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Latest Binding Stories

Undiscovered Drugs In The Novemdecillions
2012-06-07 05:55:06

Connie K. Ho for redOrbit.com Novemdecillion — now that´s a huge number. A report published in the American Chemical Society journal Chemical Neuroscience estimates that scientists have barely synthesized one tenth of one percent of the possible medicines that could be made. The estimate of these “small molecules” is potentially 1 novemdecillion, which equals a one with 60 zeros or 1 million billion billion billion billion billion billion. The American Chemical...

2012-01-02 11:54:59

The binding of proteins to various substrates in a biological system is a basic but essential process to maintain the function of living things. The mechanisms underlying protein binding have been the focus of theoretical and experimental research for many years. Many mechanisms have been proposed and characterized, including "lock and key", "induced fit", "population shift" and "fly-casting". The recently discovered "fly-casting" mechanism allows a protein chain to unfold and extend to reach...

2010-06-29 06:00:00

BERLIN and BURLINGTON, Mass., June 29 /PRNewswire/ -- caprotec bioanalytics GmbH announced today that it has successfully completed a research collaboration with F. Hoffmann-La Roche, Basel, Switzerland. Under the collaboration research agreement, caprotec used its proprietary CCMS (Capture Compound Mass Spectrometry) technology to analyze the binding characteristics and interaction of one undisclosed drug candidate with its human target proteins. To identify selectively interacting...

2009-08-19 12:38:33

Computational biologists at the University of Pittsburgh School of Medicine have shown that proteins have an intrinsic ability to change shape, and this is required for their biological activity. This shape-changing also allows the small molecules that are attracted to a given protein to select the structure that permits the best binding. That premise could help in drug discovery and in designing compounds that will have the most impact on protein function to better treat a host of...

2008-02-21 13:45:00

Bacteria can be made to spin spider silk Biological and medical research is on the threshold of a new era based on better understanding of how large organic molecules bind together and recognise each other. There is great potential for exploiting the molecular docking processes that are commonplace in all organisms to develop new drugs that act more specifically without adverse side effects, and construct novel materials by mimicking nature. A recent workshop on Biosupramolecular Chemistry...

2006-06-25 20:44:20

By Noah Barkin BERLIN (Reuters) - When a German magazine ran a story about new efforts to ban public smoking, the reactions of many of its non-smoking readers were fierce -- and surprising. "I don't want to be deprived of the relaxed company of smokers in restaurants and bars," wrote David Harnasch of Freiburg in a letter to Der Spiegel weekly. "If my clothes stink of smoke, I can wash them -- where exactly is the problem?" Yvonne Deim from Munich wrote: "Sitting in a smoke-filled...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.