Quantcast

Latest Biochemistry of Alzheimer's disease Stories

2008-03-12 19:31:21

Do you remember the seventh song that played on your radio on the way to work yesterday? Most of us don't, thanks to a normal forgetting process that is constantly "cleaning house" "“ culling inconsequential information from our brains. Researchers at the Buck Institute now believe that this normal memory loss is hyper-activated in Alzheimer's disease (AD) and that this effect is key to the profound memory loss associated with the incurable neurodegenerative disorder. Last year, this...

2006-07-10 19:13:46

CHICAGO (Reuters) - Sampling spinal fluid for a protein that makes up the plaques that clog the brains of Alzheimer's disease patients may help diagnose the mind-wasting disease, researchers said on Monday. As plaques build up in the brain, levels of the protein -- A beta 42 -- are thought to decline elsewhere in the body, including the spinal fluid, according to the study appearing in the Archives of Neurology. Other than giving suspected Alzheimer's patients mental tests, a...

2006-03-15 14:00:00

LONDON (Reuters) - Scientists have identified a substance in the brains of mice that causes memory loss, which could be a target for drugs to treat patients with Alzheimer's disease. Using genetically-engineered mice that developed memory loss similar to people with Alzheimer's, the researchers discovered that it was caused by a protein complex. "Finding the specific cause of memory loss and cognitive decline gives scientists a protein complex to target," said Professor Karen Ashe of the...

2006-01-10 11:20:00

By Anne Harding NEW YORK (Reuters Health) - As body fat increases, so do blood levels of a protein fragment linked to Alzheimer's disease, a new study shows, which may begin to explain the recently reported association between obesity and the brain-wasting disease. "We found that obesity by itself, even in otherwise healthy middle-aged people, is associated with elevated levels of the amyloid peptide that builds up and causes Alzheimer's," Dr. Sam Gandy, director of the Farber Institute for...

2005-12-02 11:08:56

San Francisco, Calif. (December 1, 2005)-- Researchers at the Gladstone Institute of Neurological Disease have identified a potential new way to stop brain cell death related to Alzheimer's disease. Working with cell cultures, the scientists investigated how amyloid beta proteins, which build up in the brain tissue of people with Alzheimer's disease, kill neurons. The cell cultures were established from brain tissue of laboratory rats. Study findings showed that amyloid beta could be...

2005-10-06 17:54:14

Alzheimer's disease, a complex neurological disorder, has as one of its hallmarks the presence of senile plaques in the brains of affected individuals. These senile plaques are rich in a toxic amyloid peptide termed Aâ. The mechanisms underlying the production of Aâ are complex, but it is known that this peptide is derived from a larger precursor known as the amyloid precursor protein (AâPP). Interestingly, and of potential therapeutic...

2005-09-20 15:55:39

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease. "What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already...

2005-07-14 13:03:49

By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - Tests on mice suggest the brain damage caused by Alzheimer's disease may be at least partly reversible, researchers reported Thursday. Their genetically altered mice regained the ability to navigate mazes after the genes that caused their dementia were de-activated. This suggests that the brain damage caused by Alzheimer's is not permanent, they wrote in their report, published in the journal Science. "I was...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
Related