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Latest Biochemistry of Alzheimer's disease Stories

2011-07-07 06:52:34

(Ivanhoe Newswire) "“ The little-studied amyloid peptide may be promoting Alzheimer's disease (AD), according to this study. Their findings show that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to aggregate than other agents studied earlier. An irreversible, progressive brain disease affecting millions worldwide, Alzheimer's disease is devastating for its victims, robbing them of their memory and cognitive skills and ultimately of their lives. Even...

2011-07-04 12:39:41

Highly aggregative and neurotoxic amyloid peptide A-beta-43 points the way to new approaches for AD diagnosis and treatment Researchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease (AD). Their surprising findings reveal that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to aggregate than amyloidogenic agents studied in earlier research,...

2011-07-03 12:35:02

Highly aggregative and neurotoxic amyloid peptide Abeta43 points the way to new approaches for AD diagnosis and treatmentTokyo, July 4, 2011 - (ACN Newswire) - Researchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease (AD). Their surprising findings reveal that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to aggregate than amyloidogenic...

2011-06-29 18:13:55

Overexpression of gene is linked with Alzheimer's disease and down syndrome Chronic stress has long been linked with neurodegeneration. Scientists at USC now think they may know why. The study, which has tremendous implications for understanding and treating Alzheimer's disease, was published in the June issue of The FASEB Journal (the Journal of the Federation of American Societies for Experimental Biology). Corresponding author Kelvin J. A. Davies, the James E. Birren Chair at the USC Davis...

2011-06-15 06:20:00

(Ivanhoe Newswire) -- A unique brain scanner is used to allow the assessment of amyloid plaques and neurofibrillary tangles- the hallmarks of Alzheimer's disease- in adults with Down syndrome. This finding may offer a new clinical tool to help diagnose dementia in adults with Down syndrome. Adults with this disorder develop Alzheimer's-like plaque and tangle deposits early, often before the age of 40. Previously, the only way to physically detect these abnormal proteins in this population was...

2011-06-14 01:33:52

In one of the first studies of its kind, UCLA researchers used a unique brain scan to assess the levels of amyloid plaques and neurofibrillary tangles "” the hallmarks of Alzheimer's disease "” in adults with Down syndrome. Published in the June edition of the Archives of Neurology, the finding may offer an additional clinical tool to help diagnose dementia in adults with Down syndrome, a genetic disorder caused by the presence of a complete or partial extra copy of chromosome...

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2011-06-07 09:33:44

In what they are calling a new direction in the study of Alzheimer's disease, UC Santa Barbara scientists have made an important finding about what happens to brain cells that are destroyed in Alzheimer's disease and related dementias. The results are published in the online version of The Journal of Biological Chemistry. Stuart Feinstein, professor of Molecular, Cellular and Developmental Biology, senior author, and co-director of UCSB's Neuroscience Research Institute, explained: "With...

2011-05-26 20:45:04

Stress hormones lead to Alzheimer-like protein modifications Stress promotes neuropathological changes that are also seen in Alzheimer's disease. Scientists from the Max Planck Institute of Psychiatry in Munich have discovered that the increased release of stress hormones in rats leads to generation of abnormally phosphorylated tau protein in the brain and ultimately, memory loss. Protein deposits in nerve cells are a typical feature of Alzheimer's disease: the excessive alteration of the tau...

2011-05-12 04:00:00

SUN CITY, Ariz., May 12, 2011 /PRNewswire/ -- Researchers at Banner Sun Health Research Institute (BSHRI) has found further evidence linking copper to the increased probability of developing Alzheimer's disease, according to a study published in the current issue of the International Journal of Alzheimer's Disease, vol. 2011, Article ID 987023. While the cause and progression of Alzheimer's disease are not completely understood, researchers believe the dementia is associated with plaques...

2011-05-02 19:45:01

Higher levels of cell chatter boost amyloid beta in the brain regions that Alzheimer's hits first, researchers at Washington University School of Medicine in St. Louis report. Amyloid beta is the main ingredient of the plaque lesions that are a hallmark of Alzheimer's. These brain regions belong to a network that is more active when the brain is at rest. The discovery that cells in these regions communicate with each other more often than cells in other parts of the brain may help explain...