Quantcast

Latest Biochemistry of Alzheimer's disease Stories

2011-05-02 19:38:29

A protein associated with Alzheimer's disease clogs several motors of the cell transport machinery critical for normal cell division, leading to defective neurons that may contribute to the memory-robbing disease, University of South Florida researchers report. In a new study published online in the journal Cell Cycle, scientists at the USF Health Byrd Alzheimer's Institute. the Florida Alzheimer's Disease Research Center, and Indiana University also suggest that the protein beta amyloid...

2011-03-30 17:01:50

Potential to identify at-risk individuals may open the door for preventive therapies Researchers using two brain-imaging technologies have found that apparently normal older individuals with brain deposits of amyloid beta "“ the primary constituent of the plaques found in the brains of Alzheimer's disease patients "“ also had changes in brain structure similar to those seen in Alzheimer's patients. Results of the study, which has received early online publication in the Annals of...

2011-03-04 12:46:00

LA JOLLA, Calif., March 4, 2011 /PRNewswire/ -- Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease -- pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment. The study was published online in The Journal of...

2011-02-16 15:36:53

Max Planck study raises hopes for the development of effective therapies Amyloid-beta and tau protein deposits in the brain are characteristic features of Alzheimer disease. The effect on the hippocampus, the area of the brain that plays a central role in learning and memory, is particularly severe. However, it appears that the toxic effect of tau protein is largely eliminated when the corresponding tau gene is switched off. Researchers from the Max Planck Research Unit for Structural...

2011-02-16 15:28:08

LA BioMed study finds damaging accumulation of tau proteins removed Increasing puromycin-sensitive aminopeptidase, the most abundant brain peptidase in mammals, slowed the damaging accumulation of tau proteins that are toxic to nerve cells and eventually lead to the neurofibrillary tangles, a major pathological hallmark of Alzheimer's disease and other forms of dementia, according to a study published online in the journal, Human Molecular Genetics. Researchers found they could safely...

2011-01-18 23:16:01

Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease, according to a study in the January 19 issue of JAMA. "Both diagnosis and treatment of Alzheimer disease (AD) are hampered by the lack of noninvasive biomarkers of the underlying pathology. Between 10 percent and 20 percent...

2011-01-12 15:49:34

Study in mice indicates disease's underlying causes and finds compounds that normalize the Alzheimer's brain A Blanchette Rockefeller Neurosciences Institute (BRNI) study published today in the Journal of Neuroscience reveals underlying causes for the degeneration of synapses in Alzheimer's Disease and identifies promising pharmaceutical solutions for the devastating condition that affects more than 5 million people in the United States. The BRNI study is the first to achieve fundamental...

2011-01-11 16:01:00

Study in Mice Indicates Disease's Underlying Causes and Finds Compounds That Normalize the Alzheimer's Brain MORGANTOWN, W.Va., Jan. 11, 2011 /PRNewswire-USNewswire/ -- A Blanchette Rockefeller Neurosciences Institute (BRNI) study published today in the Journal of Neuroscience reveals underlying causes for the degeneration of synapses in Alzheimer's Disease and identifies promising pharmaceutical solutions for the devastating condition that affects more than 5 million people in the United...

2010-12-21 07:22:28

(Ivanhoe Newswire) "“ People at known high risk for Alzheimer's disease develop abnormal brain function even before the appearance of amyloid plaques that are characteristic of the disease. Scientists now can see the difference using an MRI scanner. The MRI revealed that these high risk patients had a particular form of the apolipoprotein E (APOE) gene called APOE4. The findings suggest that the gene variant affects brain function long before the brain begins to accumulate amyloid...

2010-12-16 14:54:06

APOE4 genotype linked to functional changes prior to formation of senile plaques People with a known, high risk for Alzheimer's disease develop abnormal brain function even before the appearance of telltale amyloid plaques that are characteristic of the disease, according to a new study. Researchers at Washington University School of Medicine in St. Louis report in the Dec. 15 issue of The Journal of Neuroscience that these patients had a particular form of the apolipoprotein E (APOE) gene...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
Related