Latest Biological membrane Stories
A team of Penn State researchers has developed a simple artificial cell with which to investigate the organization and function of two of the most basic cell components: the cell membrane and the cytoplasm--the gelatinous fluid that surrounds the structures in living cells.
Imagine having one polymer and one small molecule that instantly assemble into a flexible but strong sac in which you can grow human stem cells, creating a sort of miniature laboratory. And that sac, if used for cell therapy, could cloak the stem cells from the human bodyâ€™s immune system and biodegrade upon arriving at its destination, releasing the stem cells to do their work.
Scientists have known for more than a decade that a protein associated with the HIV virus is good at crossing cell membranes, but they didnâ€™t know how it worked. A multidisciplinary team from the University of Illinois has solved the mystery, and their findings could improve the design of therapeutic agents that cross a variety of membrane types.
By Otter, W K den Shkulipa, S A ABSTRACT The flow behavior of lipid bilayer membranes is characterized by a surface viscosity for in-plane shear deformations, and an intermonolayer friction coefficient for slip between the two leaflets of the bilayer.
It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered. New research from Rice University offers clues, showing for the first time how salicylate -- an active metabolite of aspirin -- weakens lipid membranes. Researchers believe these mechanical changes disrupt the lining of the stomach, which functions to protect underlying tissue from the acidic contents of the gut. By a...
The structure of the membrane protein NhaA has been revealed by researchers at the Hebrew University of Jerusalem and the Max Planck Institute of Germany.
A protein that provides a vital passage through a bacterium's outer cell wall will misfold and malfunction if that wall is built of the 'wrong' material, scientists at The University of Texas Medical School at Houston report in a finding that has long-term implications for understanding diseases caused by misfolded proteins such as cystic fibrosis, Alzheimer's disease, and mad cow disease.
Phospholipid bilayers serve as the framework in biological membranes in which other components are embedded. Fundamental not only in biology, lipid bilayers are also essential in applications such as biosensors and nanoreactors.