Latest Biomolecules Stories

2010-04-29 12:56:48

'Smart' catalysts programmed to recognize specific molecular shape Using a rare metal that's not utilized by nature, Rice University chemists have created a synthetic enzyme that could help unlock the identities of thousands of difficult-to-study proteins, including many that play key roles in cancer and other diseases. The research was published online this week in the Journal of the American Chemical Society. "We have combined the chemical capabilities of rhodium with what biology already...

2010-03-25 09:35:00

Suspecting that a particular protein in tuberculosis was likely to be vital to the bacteria's survival, Johns Hopkins scientists screened 175,000 small chemical compounds and identified a potent class of compounds that selectively slows down this protein's activity and, in a test tube, blocks TB growth, demonstrating that the protein is indeed a vulnerable target. This class of chemical compounds attacks TB by inhibiting methionine aminopeptidase (MetAP), an essential enzyme found in...

2010-03-15 16:11:00

MADRID, March 15 /PRNewswire/ -- Centocor Ortho Biotech Products has informed PharmaMar SA (Grupo Zeltia, ZEL.MC) that the regulatory authorities in Israel, Panama and Ukraine have approved Yondelis(R) for advanced soft tissue sarcoma (STS) in adults. Furthermore, the authorities in Paraguay and Azerbaijan have approved the drug for platinum-sensitive recurrent ovarian cancer (ROC). Yondelis is already approved for STS in Paraguay and Azerbaijan. The European Commission approved...

2010-02-27 09:04:18

A team of Michigan State University scientists - using a new cooling method they created - has uncovered the inner workings of a key iron-containing enzyme, a discovery that could help researchers develop new medicines or understand how enzymes repair DNA. Taurine/alpha-ketoglutarate dioxygenase, known as TauD, is a bacterial enzyme that is important in metabolism. Enzymes in this family repair DNA, sense oxygen and help produce antibiotics. Specifically, the MSU team was interested in how...

2010-02-22 10:52:59

Have you seen a spotted plaice? Probably. However, marine biologist Helen Nilsson Sköld at the University of Gothenburg is the first person to research the spotted insides of plaice. Many species of animal have skin or fur with intricate pigmentation patterns, which they use for camouflage, communication, regulation of body heat and protection against the sun. A study conducted by researchers at the Department of Marine Ecology at the University of Gothenburg has found that several...

2010-02-19 10:32:40

It is not unusual to hear people blame their metabolism after gaining a few pounds. But changes in metabolism "“ the process that shapes how our bodies turn food into energy -- can have much more sinister effects than making it hard to fit into your favorite jeans. In fact, differences in metabolic rates are known to exist between normal cells and tumor cells, though the mechanism behind it is unclear. Now new research from the University of North Carolina at Chapel Hill suggests that...

2010-02-16 10:54:05

Chemists in Mlheim devise a new way of optimizing enzymes for industrial applications Engineers are unlikely to tinker with the cooling system if they want to increase the size of an engine. Yet chemists at the Max Planck Institute for Coal Research have adopted an approach similar to this in their efforts to optimize an enzyme for practical applications. They substituted two amino acids at a site relatively distal to the biocatalyst's binding pocket, the location where the chemical reaction...

2010-02-16 09:56:33

Structure will help MU researchers determine function, develop drugs to inhibit enzyme If subway terminals didn't exist and people had to exit subway stations to switch subway lines, transit time would increase. People also may encounter distractions, such as grabbing a cup of coffee, instead of getting on the other line. Molecules also use "terminals" to save transit time during enzyme-catalyzed processes. Using advanced X-radiation techniques, University of Missouri researchers were able to...

2010-02-16 07:56:43

Researchers report that they have discovered "“ and now know how to exploit "“ an unusual chemical reaction mechanism that allows malaria parasites and many disease-causing bacteria to survive. The research team, from the University of Illinois, also has developed the first potent inhibitor of this chemical reaction. The findings appear in the Proceedings of the National Academy of Sciences. "There is an urgent need for new drugs to combat malaria and bacterial diseases such as...

2010-02-04 06:00:00

PRINCETON, NJ, Feb. 4 /PRNewswire/ - DNP Green Technology has acquired a controlling stake in Sinoven Biopolymers Inc., a private US company. Under the terms of the agreement, Sinoven Biopolymers will operate as a subsidiary of DNP Green Technology with a sales office in Philadelphia, PA and a manufacturing and formulation development facility in Shanghai, China. Sinoven Biopolymers has proprietary technology for modifying polybutylene succinate (PBS), giving it unique properties that other...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'