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Latest Biomolecules Stories

2008-09-28 00:00:17

By The Associated Press DES MOINES (AP) - Critics are complaining that state environmental officials have done little about an outbreak of toxic algae that threatened the safety of drinking water in Iowa's largest city and posed a risk to swimmers at a west-central Iowa lake.They said the blue-green algae, or cyanobacteria, was found at Black Hawk Lake near Lake View, and that levels recorded just after Labor Day were seven times more than an internationally recognized benchmark for safe...

2008-09-16 15:00:38

A U.S. scientist says a combination of the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit for relapsed ovarian cancer. University of California-Irvine Associate Professor Bradley Monk said the combination, which does not include a platinum drug, challenges the current standard of treatment for women whose cancer recurs at least 6 months after first-line treatment. "This trial, which included almost two-thirds such women, challenges this traditional...

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2008-09-12 14:33:47

Scientists at Stanford University Medical Center reported Thursday that an enzyme that helps the body metabolize alcohol might also limit injury during a heart attack.  They also found that an experimental drug might amplify this protective effect, the researchers said. The scientists hope their study, performed in rats, may one day lead to a drug that would protect those suffering from the chest pain that often precedes a heart attack. Such a drug may also have uses during coronary...

2008-09-11 15:00:11

Marauding molecules cause the tissue damage that underlies heart attacks, sunburn, Alzheimer's and hangovers. But scientists at the Stanford University School of Medicine say they may have found ways to combat the carnage after discovering an important cog in the body's molecular detoxification machinery. The culprit molecules are oxygen byproducts called free radicals. These highly unstable molecules start chain reactions of cellular damage -- an escalating storm that ravages healthy...

2008-09-11 03:00:19

By Manian, Avinash P Lenninger, Margit; Bechtold, Thomas; Steinlechner, Erik Abstract The liming propensity of a woven cellulosic substrate is investigated as a function of substrate characteristics and of different parameters in the test environment. The results from the linting propensity tests parallel those observed in liquid-solid extraction processes, where solutes are extracted from a matrix of other insoluble solids by selective dissolution in a liquid. The equation quantifying...

2008-08-20 12:00:27

U.S.-led researchers say they have created a new model of catalyst design that challenges current ideas about how catalysts function. The study also suggests a method for designing new catalysts. "Catalysts are molecules that speed up chemical reactions without participating in them," the researchers said, noting thousands of industrial and biological processes rely on catalysts. In the human body, enzymes catalyze nearly every reaction. "The Holy Grail of enzyme catalysis and the...

2008-08-06 12:00:00

University of Georgia researchers suggest herbs and spices are potent inhibitors of tissue damage and inflammation caused by high levels of blood sugar. Study co-author James Hargrove said that when blood sugar levels are high, a process known as protein glycation occurs in which the sugar bonds with proteins to eventually form what are known as advanced glycation end products, known as AGE compounds. These compounds activate the immune system, resulting in the inflammation and tissue damage...

2008-07-25 03:00:40

By Kubiak, Karina Nowak, Wieslaw ABSTRACT Nitrile hydratase (NHase) is an enzyme used in the industrial biotechnological production of acrylamide. The active site, which contains nonheme iron or noncorrin cobalt, is buried in the protein core at the interface of two domains, alpha and beta. Hydrogen bonds between betaArg-56 and alphaCys-114 sulfenic acid (alphaCEA114) are important to maintain the enzymatic activity. The enzyme may be inactivated by endogenous nitric oxide (NO) and...

2008-07-07 15:00:13

U.S. scientists say they have produced synthetic molecules that can emulate enzyme behaviors. Many jobs require highly specialized catalysts and finding one in just the right shape to connect with certain molecules can be difficult, the Ohio State University chemists said, noting enzymes in the human body that help us digest food can utilize shape-shifting to suit the task at hand. Now the Ohio State researchers say they have created a synthetic catalyst that can fold its molecular...

2008-07-02 16:14:38

COLUMBUS, Ohio -- When chemists want to produce a lot of a substance -- such as a newly designed drug -- they often turn to catalysts, molecules that speed chemical reactions. Many jobs require highly specialized catalysts, and finding one in just the right shape to connect with certain molecules can be difficult.  Natural catalysts, such as enzymes in the human body that help us digest food, get around this problem by shape-shifting to suit the task at hand. Chemists have made little...


Word of the Day
out-herod
  • In the phrase to out-herod Herod, to be more violent than Herod (as represented in the old mystery plays); hence, to exceed in any excess of evil.
Herod refers to 'Herod the Great,' a Roman client king and 'a madman who murdered his own family and a great many rabbis.' According to the OED, the term is 'chiefly with allusion to Shakespeare's use' in Hamlet.
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