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Latest Biomolecules Stories

2008-07-02 16:14:38

COLUMBUS, Ohio -- When chemists want to produce a lot of a substance -- such as a newly designed drug -- they often turn to catalysts, molecules that speed chemical reactions. Many jobs require highly specialized catalysts, and finding one in just the right shape to connect with certain molecules can be difficult.  Natural catalysts, such as enzymes in the human body that help us digest food, get around this problem by shape-shifting to suit the task at hand. Chemists have made little...

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2008-03-24 14:15:00

Scientists succeed in designing artificial enzymes that also undergo 'evolution in a test tube'Mankind triumphed in a recent 'competition' against nature when scientists succeeded in creating a new type of enzyme for a reaction for which no naturally occurring enzyme has evolved. This achievement opens the door to the development of a variety of potential applications in medicine and industry. Enzymes are, without a doubt, a valuable model for understanding the intricate works of nature....

2007-09-15 03:00:53

By Bengmark, Stig ABSTRACT. Background: High levels of glycated and lipoxidated proteins and peptides in the body are repeatedly associated with chronic diseases. These molecules are strongly associated with activation of a specific receptor called RAGE and a long-lasting exaggerated level of inflammation in the body. Methods: PubMed reports over 5000 papers plus > 13,500 articles about the related HbA^sub 1c^, most of them published in the past 5 years. Most of the available abstracts...

2007-06-12 03:00:10

By Masubuchi, Yasuhiro Horie, Toshiharu Cytochrome P450 (P450) enzymes oxidize xenobiotics into chemically reactive metabolites or intermediates as well as into stable metabolites. If the reactivity of the product is very high, it binds to a catalytic site or sites of the enzyme itself and inactivates it. This phenomenon is referred to as mechanism-based inactivation. Many clinically important drugs are mechanism-based inactivators that include macrolide antibiotics, calcium channel...

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2007-03-20 08:20:00

Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. Their results provide insight into what may have been the first self-replicating molecule to arise billions of years ago on the evolutionary path toward the emergence of life. In all forms of life known today, the synthesis of DNA and RNA molecules is carried out by enzymes made of...

2007-01-07 21:00:10

By Rajen M. BLOOD purification is a very traditional medicine concept, and very prevalent in the east. Cuci darah as we call it here is common amongst all major races. The roots of the concept arise from the Indian traditonal system of healing - Ayurveda, Chinese traditional medicine and in Malay medicine. Blood is seen as the medium constantly flowing through our bodies. It supplies life giving nutrients, blood and carries away metabolic wastes. Some of these are toxins which...

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2006-08-23 08:59:08

Water, that molecule-of-all-trades, is famous for its roles in shaping the Earth, sustaining living creatures and serving as a universal solvent. Now, researchers at the University of Michigan and the Academy of Sciences of the Czech Republic have uncovered two previously unknown roles for water in RNA enzymes, molecules which themselves play critical roles in living cells and show promising medical applications. The researchers' findings will be published online in the Proceedings of the...

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2006-05-15 14:15:00

Two laboratories at Penn State set out to show how an obscure undersea microbe metabolizes carbon monoxide into methane and vinegar. What they found was not merely a previously unknown biochemical process -- their discovery also became the inspiration for a fundamental new theory of the origin of life on Earth, reconciling a long-contentious pair of prevailing theories. This new, "thermodynamic" theory of evolution improves upon both previous theories by proposing a central role for energy...

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2006-03-16 06:11:40

NASA -- How does chemistry become biology? Solving this question is important for research into life's origins, and also for the search for life elsewhere in the universe. In this interview, Dimitar Sasselov, professor of astronomy at Harvard University, describes a new comprehensive study that will try to figure out how chemical systems cross over into the world of the living. --- Interview with Dimitar Sasselov Astrobiology Magazine (AM): Harvard University is funding a new study called...

2005-10-24 20:22:26

CHAPEL HILL "“ An enzyme inside a bacterium that grows in the soil of potato fields can -- in a split second -- break down residues of a common powerful pesticide used for killing worms on potatoes, researchers have found. That may be expensive for farmers but lucky for the environment because University of North Carolina at Chapel Hill scientists have now discovered that if that particular enzyme weren't there, it would take 10,000 years for just half of the widely used pesticide to...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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