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Latest Bipolar disorders research Stories

neurons from induced pluripotent stem cells
2014-03-26 05:25:31

[ Watch the Video: First Stem Cell Study of Bipolar Disorder Yields Promising Results ] April Flowers for redOrbit.com - Your Universe Online Bipolar disorder affects 200 million people globally, and yet there are so many questions surrounding the condition. Why are individuals with bipolar disorder prone to manic highs and deep, depressed lows? If there is no single gene to blame, why does bipolar disorder run so strongly in families? And why, with the enormous number of people...

2012-10-15 14:35:17

A new genetic study in Biological Psychiatry One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies. Scientists at King's College London, Institute of Psychiatry have now performed one of the largest ever genetic replication studies of bipolar affective disorder, with 28,000 subjects recruited from 36 different research centers. Their findings provide compelling evidence that the chromosome 3p21.1 locus contains a common genetic risk...

2012-07-03 10:59:06

Schizophrenia or bipolar disorder in first-degree relatives, such as parents or siblings, may be associated with increased risk of autism spectrum disorder (ASD), according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication. Patrick F. Sullivan, M.D., F.R.A.N.Z.C.P, of the University of North Carolina at Chapel Hill, and colleagues used population registers in Sweden and Israel to examine whether a family history of schizophrenia, bipolar...

2012-05-10 14:03:47

New genetic findings reported in Biological Psychiatry These findings are not about the classic story of gift-giving, although the MAGI genes (officially named membrane associated guanylate kinase, WW and PDZ domain containing proteins) do influence brain function in important ways. MAGI1 and MAGI2 are genes that code for the MAGI proteins. These proteins influence the development and function of synapses in the brain, the junctions where communication between nerve cells occurs....

2011-10-24 22:50:17

Researchers at the University of Leeds investigating the genetic causes of bipolar disorder have identified two new drugs — one of which has already been found safe in clinical trials — that may be effective in treating the disorder. Bipolar disorder is characterized by mood swings between mania and depression. Like autism, it is thought to be a spectrum of disorders and, although its causes are not well understood, it seems to run in families and is thought to be caused by...

2011-05-24 18:46:12

A new study by motor control and psychology researchers at Indiana University suggests that postural control problems may be a core feature of bipolar disorder, not just a random symptom, and can provide insights both into areas of the brain affected by the psychiatric disorder and new potential targets for treatment. Problems with balance, postural control and other motor control issues are frequently experienced by people with mood and psychiatric disorders such as bipolar disorder and...

2011-03-03 12:56:48

A new study provides fascinating insight into the genetic basis of bipolar disorder, a highly heritable mood disorder characterized by recurrent episodes of mania and depression. The research, published by Cell Press online February 24 in the American Journal of Human Genetics, identifies a previously unrecognized susceptibility factor for bipolar disorder. Genome-wide association studies (GWAS) provide a way to systematically sort through all the DNA of many individuals in order to identify...

2011-02-23 16:38:04

Understanding the genetics of bipolar disorder could lead to new treatments, but identifying specific genetic variations associated with this disorder has been challenging. A new study in Biological Psychiatry implicates a brain protein called Piccolo in the risk for inheriting bipolar disorder. In the orchestra of neuronal proteins, Piccolo is a member of a protein family that includes another protein called Bassoon. Piccolo is located at the endings of nerve cells, where it contributes to...

2011-02-16 15:55:31

Lithium, introduced in the late 1940's, was the first "wonder drug" in psychiatry. It was the first medication treatment for the manic and depressive episodes of bipolar disorder and it remains among one of the most effective treatments for this disorder. In the past 15 years, as molecular mechanisms underlying the treatment of bipolar disorder began to emerge, basic research studies conducted in animals began to identify neuroprotective and perhaps neurotrophic effects of this important...

2010-06-17 15:06:35

Possible mechanism identified for how lithium treats bipolar disorcer Lithium has been established for more than 50 years as one of the most effective treatments for manic depression, clinically termed bipolar disorder. However, scientists have never been entirely sure exactly why it is beneficial. Now, new research from Cardiff University scientists suggests a possible mechanism for why Lithium works, opening the door for better understanding of the illness and potentially more effective...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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