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Latest Bisphosphonate Stories

2011-03-11 13:37:28

Postmenopausal women have a new health message to hear. Two annual dental checkups aren't enough. Older women need more, according to research findings from the Case Western Reserve University School of Dental Medicine and the Cleveland Clinic. That message comes from a comparison study of women on and off bone-strengthening bisphosphonate therapies for osteoporosis. Leena Palomo, assistant professor of periodontics from the dental school, and Maria Clarinda Beunocamino-Francisco from the...

2011-02-23 01:50:42

Older women who used bisphosphonates (medications that prevent loss of bone mass) for five years or more were more likely to experience "atypical" fractures involving the femoral shaft (bone in the leg that extends from the hip to the knee) or subtrochanteric (fractures in the bone just below the hip joint), compared to women with less usage. However, the absolute risk of these "atypical" fractures was low and bisphosphonate use was associated with a reduced risk of typical osteoporotic...

2011-02-14 15:54:40

A commonly prescribed osteoporosis drug is associated with a slightly elevated risk of developing the rare, but serious condition, osteonecrosis of the jaw; nonetheless the risk remains extremely low. These findings are published online in the Journal of Dental Research, the official journal of the International and American Associations for Dental Research. Although the findings are provocative, study authors say they should be carefully considered against the large benefit of these drugs to...

2011-02-11 21:25:22

Results may have an important impact to the developing of better definitions for ONJ Osteonecrosis of the jaw (ONJ) is a debilitating bone condition that affects the jaws and occurs as a result of reduced local blood supply to the bone. The literature in this area has been severely limited since most investigations cannot evaluate sufficient numbers of afflicted individuals to accurately determine the incidence of the disease and associated risk factors. Today, the International and American...

2011-02-02 15:13:35

Australian clinical researchers have noted an extraordinary and unexpected benefit of osteoporosis treatment "“ that people taking bisphosphonates are not only surviving well, better than people without osteoporosis, they appear to be gaining an extra five years of life. Associate Professor Jacqueline Center and Professor John Eisman, from Sydney's Garvan Institute of Medical Research, based their findings on data from the long running Dubbo Osteoporosis Epidemiology Study*. Out of a...

2011-01-17 16:00:00

ROCKVILLE, Md., Jan. 17, 2011 /PRNewswire-USNewswire/ -- In an update to its 2002 recommendation, the U.S. Preventive Services Task Force (USPSTF) now recommends that all women ages 65 and older be routinely screened for osteoporosis. This is the first final recommendation statement to be published since the USPSTF implemented a new process in July 2010 in which all of its draft recommendation statements are posted for public comment on the USPSTF website prior to being issued in final...

2011-01-14 19:08:51

A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine. Their findings, recently published in Cell Metabolism, confirm a long-held speculation that the childhood infection is an environmental trigger for the disease and reveal how the viral gene contributes to the development of its characteristic bone lesions. "Our earlier work showed that bone cells called...

2010-12-09 19:59:15

The long-awaited results of the Adjuvant Treatment with Zoledronic Acid in Stage II/III Breast Cancer, the AZURE trial, will be presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held here Dec. 8-12. "Adjuvant use of bisphosphonates like zoledronic acid is widespread among women with breast cancer, and the results of this trial will help answer many questions as well invite new ones," said Robert Coleman, M.D., professor of medical oncology at the University of...

2010-12-03 18:09:00

EAST HANOVER, N.J., Dec. 3, 2010 /PRNewswire/ -- A newly published study in the Lancet suggested that a first-line treatment regimen including Zometa® (zoledronic acid) significantly improved overall survival (OS) and progression-free survival (PFS) in newly diagnosed multiple myeloma patients compared with a regimen that included oral clodronate. The impact on survival was independent of the effect of Zometa on bone complications (also known as skeletal-related events...

2010-11-24 08:37:00

NEW YORK, Nov. 24, 2010 /PRNewswire/ -- See video from International Osteoporosis Foundation at: http://www.thenewsmarket.com/Releases/StoryDetailPage.aspx?GUID=8267be3a-b41c-4c99-8ac8-85195799b081# Leading experts from the European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF) have published a position paper on the association between subtrochanteric femoral (upper thigh bone) fractures and...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.