Latest Blastoma Stories

A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study. Boulder, CO (PRWEB) May 09, 2013 A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing...

Voices Against Brain Cancer (VABC) responds to an article posted by Bioscience Technology detailing how the blockage of molecular pathways in the brain may be a contributing factor to the development of brain tumors. Bohemia, NY (PRWEB) April 05, 2013 On April 5, 2013, Voices Against Brain Cancer (VABC) responds to an article posted by Bioscience Technology detailing how the blockage of molecular pathways in the brain could be a contributing factor in the development of brain tumors. The...

A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network (UHN), has discovered a new type of retinoblastoma, a rapidly developing eye cancer that affects very young babies– a finding that can immediately change clinical practice and optimize care for these children. The finding, published online today in Lancet Oncology, is a breakthrough in recognizing that a single cancer gene (an oncogene) drives...

Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave. The study, which appears in the current issue of the Journal of Biological Chemistry, focuses on the nontraditional lifestyle of Retinoblastoma tumor suppressor proteins, which could lead to new ways to treat cancer. “Retinoblastoma proteins are unique in that they use controlled destruction to do their jobs in a timely but restrained fashion,” said Liang Zhang, a...

Sanford-Burnham Medical Research Institute Brain tumors arising from different cell types might require different—and more personalized—treatment approaches. Cancers arise when a normal cell acquires a mutation in a gene that regulates cellular growth or survival. But the particular cell this mutation happens in—the cell of origin—can have an enormous impact on the behavior of the tumor, and on the strategies used to treat it. Robert Wechsler-Reya, Ph.D., professor and...

After leukaemia and brain tumors, neuroblastoma is the most common form of cancer to affect children. A thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden, has studied a DNA method which is now used for all cases of neuroblastoma in Sweden, and which has led to more effective treatment at individual level. Neuroblastoma affects around 20 children each year, most of them under the age of two. This form of cancer, which affects the peripheral nervous system, is...

--In Genome-Wide Study, Researchers at The Children's Hospital of Philadelphia Uncover New Clues to a Childhood Cancer-- PHILADELPHIA, Sept. 4, 2012 /PRNewswire-USNewswire/ -- Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens understanding of how gene changes may make a child susceptible to this early...

Their Mexican-born counterparts at lesser risk In a large epidemiologic study, researchers at UCLA's Jonsson Cancer Center found that the children of U.S.-born Latina women are at higher risk of having retinoblastoma, a malignant tumor of the retina which typically occurs in children under six. The study, which focused on babies born in California, also found that offspring of older fathers were at greater risk for retinoblastoma, as were children born to women with sexually transmitted...

    Medulloblastoma is the most common malignant brain tumor in children.     Disseminated medulloblastoma is particularly lethal and requires extensive radiation therapy to the brain, which can cause brain damage.     An oncolytic measles virus has shown effectiveness in a new model of disseminated human medulloblastoma. A strain of measles virus engineered to kill cancer cells prolongs survival in a model of medulloblastoma that is disseminated in the fluid around the brain,...

(Ivanhoe Newswire) -- Medulloblastomas are the most common cancerous brain tumors in children. Although survival rates have improved over the years, medulloblastoma remains associated with substantial mortality, and long-term survivors often suffer debilitating effects from the intensive treatments. A team of researchers, led by Cecilia Söderberg-Nauclér and John Inge Johnsen, at the Karolinska Institutet, Sweden, has now identified a potential target for a more cancer-specific approach to...